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Alpha Adrenergic Receptors

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Year 2 Karteikarten am Alpha Adrenergic Receptors, erstellt von gina_evans0312 am 25/02/2014.
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Types of Receptors 2, each with three subclasse
A1- Mode of Action Coupled to phosphlipase Cbeta & increases cytoplasmic Ca2+
A1- Effect Vasoconstriction of smooth muscle & relaxation of the GI tract
A1- Effect on Salivary Glands Increases K+ secretion
A1- Effect on Liver Inc in glycogenlysis and gluconeogenesis
A2- Mode of Action Inhibits adenylate cyclase & reduces Ca2+/increases K+
A2- Effect Inhibits neurotransmitter & insulin release, and platelet aggregation
Effect of Agonists on the CV system Inc blood pressure (peripheral, systolic & diastolic) causing heart rate to slow
Adrenaline- Effect On Heart Inc CO, dec peripheral blood pressure & inc systolic/diastolic pressure
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