HPV Genome & Colonisation

Beschreibung

Virology (HPV) Karteikarten am HPV Genome & Colonisation, erstellt von gina_evans0312 am 14/04/2014.
gina_evans0312
Karteikarten von gina_evans0312, aktualisiert more than 1 year ago
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Erstellt von gina_evans0312 vor etwa 10 Jahre
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Zusammenfassung der Ressource

Frage Antworten
Genome Type ds DNA
Size Small
Envelope None
Location of Replication (Type of cell) Differentiating Epithelium
No of Open Reading Frames Several
Variation in ORF Expression 8-10 vary in early/late stages of infection
ORF Variation Differentiate according to different promoters/splicing
Use of Machinery Uses cells own machinery
HPV16 Infection Basal layer of cervix wall, which is differentiating
HPV16 Entry Accesses via microabrasions
Proteins for Entry Cell Surface Integrins & Haperine Sulphate Proteoglycans
Inside the Nucleus- Replication System Replicates once per cell cycle along with the cell
Inside the Nucleus- Expression of Viral Proteins Alter cell growth, causing a wart
Terminal Differentiation of the Host Cell Causes viral particle production, which are then shed
Terminal Differentiation of the Host Cell (Growth) Cell growth is abnormal, may progress to cancer, may not
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