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Research In-class Quiz

Quynh Dang 10 questions

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Questions in this quiz (10)

  1. 1A published patient case is an example of:
    1. APrimary literature- descriptive report
    2. BSecondary literature
    3. CPrimary literature- experimental study
    4. DPrimary literature- observational study
  2. 2The recent study appearing in New England of Medicine entitled "Selective Publication of antidepressant Trials and Its Influence on apparent Efficacy" was presented to illustrate presence of:
    1. AInvestigator and subject bias
    2. BSubject bias
    3. CPublication bias
    4. DAuthor (investigator) bias
  3. 3Which of the following best describes a randomized controlled trial?
    1. AProspective
    2. BRetrospective
  4. 4Which of the following BEST defines the sample patient population in a clinical trial?
    1. AInclusion criteria
    2. BExclusion criteria
    3. CStudy objective
    4. DBoth Inclusion & Exclusion criteria
    5. EAll of the above
  5. 5This type of study describes observations made of an individual patient, usually documenting an adverse drug event associated with a new agent.
    1. ACase-control study
    2. BCase Report
    3. CRandomized controlled trial
    4. DCohort study
  6. 6Careful evaluation of the “methods” section is critical; which of the following is a specific consideration when evaluating this section?
    1. AThe duration should be sufficient to evoke the Hawthorne Effect.
    2. BRandomization should account for the placebo effect.
    3. CBlinding should ensure subject and investigator objectivity.
    4. DThe literature review should be balanced.
  7. 7Many patients taking aripiprazole were shown to develop restlessness or akathisia, with a NNH of 3 for the combined adverse event. What does this mean?
    1. AFor every three patients treated with aripiprazole, one developed akathisia or restlessness.
    2. BFor every patient treated with aripiprazole that developed akathisia or restlessness, two developed akathisia or restlessness in the aripiprazole group.
    3. CFor every patient treated with aripiprazole that developed akathisia or restlessness, three developed akathisia or restlessness in the placebo group.
    4. DFor every three patients that showed improvement with aripiprazole treatment, one developed akathisia or restlessness.
  8. 8In the same trial, data were analyzed based on the number of patients after randomization. This is known as ______ analysis.
    1. APer protocol
    2. BIntent to treat
    3. CNone of the above
  9. 9Safety is ideally addressed in a study by reporting of serious adverse drug events, common adverse drug events, and the percentage that discontinues due to adverse drug events.
    1. ATrue
    2. BFalse
  10. 10Which of the following methods for group assignment is NOT random:
    1. AUsing a random number table
    2. BBy tossing a coin
    3. CAssigning every second person to the control group

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from Dr. Advani's materials
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