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DF29 Emulsions

Mer Scott 11 questions

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Questions in this quiz (11)

  1. 1[blank_start]Water-in-oil-in-water (w/o/w)[blank_end] emulsions allow for sustained release because the [blank_start]oil phase[blank_end] would act as diffusion barrier.
    1. AWater-in-oil-in-water (w/o/w)
    2. BOil-in-water-in-oil (o/w/o)
    3. Coil phase
    4. Daqueous phase
  2. 2Choice of Emulsion Type:
    1. Oral
    → [blank_start]mainly o/w[blank_end]
    – administration of oils as such or as vehicles for oilsoluble
    drugs
    2. Paraenteral
    – Intravenous
    • [blank_start]must be o/w[blank_end]
    – Intramuscular
    • [blank_start]can be o/w or w/o[blank_end]
    – Subcutaneous
    • [blank_start]can be o/w or w/o[blank_end]
    3. External
    – Widely used (creams, lotions, liniments)
    – [blank_start]o/w or w/o[blank_end]
    1. Amainly o/w
    2. Bmainly w/o
    3. Cmust be o/w
    4. Dmust be w/o
    5. Ecan be o/w or w/o
    6. Fmust be w/o
    7. Gmust be o/w
    8. Hcan be o/w or w/o
    9. Imust be o/w
    10. Jmust be w/o
    11. Kcan be o/w or w/o
    12. Lmust be o/w
    13. Mmust be w/o
  3. 3Emulsions can give extended release of the drug after injection IM or SC
    1. ATrue
    2. BFalse
  4. 4Total parenteral nutrition, TPN, is where:
    1. Aessential nutrients like carbohydrates, fats and vitamins can all be emulsified and can be administered as sterile intravenous emulsions
    2. Bessential nutrients like carbohydrates, fats and vitamins can all be emulsified and can be administered as sterile oral emulsions
    3. Cessential nutrients like carbohydrates, fats and vitamins can all be emulsified and can be administered as oral emulsions with a masked taste
  5. 5Which of these is not a property of an ideal emulsion?
    1. APours easily from bottle
    2. BCreaming is redispersed easily
    3. CChemically and physically stable for shelf life
    4. DSufficiently homogenous to extract correct dose
    5. EDifficult to spread, dries slowly
  6. 6Emulsifying agents stabilize an emulsion by [blank_start]increasing[blank_end] its kinetic stability. They are excipients which go into the [blank_start]water-oil interface[blank_end] to form a film around the [blank_start]dispersed[blank_end] globules, and include:
    1. [blank_start]Surface active[blank_end] agents
    2. [blank_start]Hydrophilic[blank_end] colloids
    3. [blank_start]Finely divided[blank_end] solids
    1. Aincreasing
    2. Bwater-oil interface
    3. Cdispersed
    4. DSurface active
    5. EHydrophilic
    6. FFinely divided
  7. 71. [blank_start]Surface tension theory[blank_end] – according to this theory, emulsification takes place by [blank_start]reduction[blank_end] of interfacial tension between the two phases.

    2. [blank_start]Repulsion theory[blank_end] – the emulsifying agent creates a film over one phase that forms globules with an electrical barrier, which [blank_start]repel[blank_end] each other. This repulsive force causes them to remain suspended in the dispersion medium.

    3. [blank_start]Physical barrier theory[blank_end] - Forming a rigid interfacial film around the dispersed phase which acts as a physical barrier to [blank_start]coalescence[blank_end].

    4. [blank_start]Viscosity theory[blank_end] – [blank_start]increase[blank_end] the viscosity of the medium, which helps create and maintain the suspension of globules of dispersed phase.
    1. ASurface tension theory
    2. BRepulsion theory
    3. CPhysical barrier theory
    4. DViscosity theory
    5. Ereduction
    6. Frepel
    7. Gcoalescence
    8. Hincrease
  8. 8Choose the incorrect statement about surfactants.
    1. AThey adsorb at the oil-water interface to form a monomolecular film
    2. BThey reduce interfacial tension
    3. CSodium lauryl sulfate, Triethanolamine stearate/oleate, Tween 80 and Span 80 are all examples
    4. DThey act as a physical barrier and have a repulsive effect
  9. 9Bancroft’s rule: The emulsifier is more soluble in the [blank_start]continuous[blank_end] phase.
    High HLB (8-16) surfactants-emulsifying agents are more soluble in [blank_start]water than in oil (O/W emulsion)[blank_end]. Low HLB (3-6) surfactant-emulsifying agents are more soluble in [blank_start]oil than water (W/O emulsion)[blank_end].
    1. Acontinuous
    2. Bdispersed
    3. Cwater than in oil (O/W emulsion)
    4. Doil than water (W/O emulsion)
  10. 10Choose the incorrect statement about hydrophilic colloids.
    1. AAdsorb at the oil-water interface to form a strong physical barrier (film) around the dispersed droplets
    2. BAct in the continuous phase of an w/o emulsion
    3. CAcacia, Tragacanth, Gelatin, and Methylcellulose are all examples
    4. DThey have an auxiliary effect; they promote stability by causing an increase in viscosity of the continuous phase
    5. EIf charged they have an additional repulsive effect

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Description
PHCY211 (Formulation) Quiz on DF29 Emulsions, created by Mer Scott on 06/05/2018.
Author
Mer Scott
Language
English
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