Quiz
MD29 Volume of Distribution
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Questions in this quiz (6)
1Choose the incorrect definition of volume of distribution.
- AVolume of distribution is the apparent volume into which a drug distributes with a concentration of that equal to plasma.
- BVolume of distribution is a constant that describes the ratio of the amount of drug in the body (A) to the concentration in the plasma (C).
- CVolume of distribution is the volume of plasma which contains the highest concentration of dose of drug at any given time.
2If the apparent volume of distribution is less than the volume of the body then we know the drug must concentrate somewhere.
- ATrue
- BFalse
3Aqueous spaces are [blank_start]physiological spaces[blank_end] because they depend on [blank_start]solubility[blank_end], and free concentration will be the [blank_start]same[blank_end]. The [blank_start]tissue spaces[blank_end] are not physiological spaces as they depend on [blank_start]partitioning[blank_end] and non specific binding.
- Aphysiological spaces
- Bsolubility
- Csame
- Dtissue spaces
- Epartitioning
4To estimate V we need to know [blank_start]A and C[blank_end]. We only know A for certain at the time of [blank_start]IV bolus infusion[blank_end]. V at time 0 is therefore equal to the [blank_start]dose[blank_end] divided by [blank_start]Cmax[blank_end].
- AIV bolus infusion
- BA and C
- Cdose
- DCmax
5If we need a plasma concentration of 10mg/L and the volume of distribution is 20L, what loading dose should we give?
- A200mg
- B600mg
- C20mg
- D60mg
6CL and V are independent.
- ATrue
- BFalse
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- Description
- PHCY211 (Medicines) Quiz on MD29 Volume of Distribution, created by Mer Scott on 27/05/2018.
- Author
- Mer Scott
- Language
- English
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- History
- Created on 27 May 2018 · updated on 27 May 2018
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