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GEGE2001 Quiz 2

Michael Jardine 10 questions

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Questions in this quiz (10)

  1. 1DNA replication:
    1. Was first observed in Darwin’s finches
    2. Must be accurate in order to transmit the genome to the next generation
    3. Is accurate in germ cells and error prone in somatic cells
    4. Must include some errors in order to produce variation
    1. A1 and 3
    2. B2 and 4
    3. C1 only
    4. D1 and 2
    5. E3 and 4
  2. 2Photoreactivation
    1. ARepairs pyrimidine dimers
    2. BUses UV light and visible light sequentially
    3. CCauses a bulge in the DNA helix
    4. DUtilises UV light for photolyase activity
    5. EDoes not occur in humans due to the use of sunscreens
  3. 3Siamese cats show a range of coat colours on a single individual because:
    1. AThey are homozygous for a missense mutation in TYR that produces a heat sensitive tyrosinase protein
    2. BCoat colour is a polygenic trait with many genotypes possible in the breed
    3. CThe breed was originally formed by the mating of a pale coat cold-climate cat and a brown coat warm-climate cat
    4. DCats arise from the fusion of 2 or more zygotes causing genetic mosaicism
    5. EFrequent somatic mutation occurs in the TYR genes when cats are not kept warm
  4. 4Microsatellites used as genetic markers because:
    1. AThey can be assayed by PCR and size separation of the DNA fragment amplified
    2. BNone of the other answers
    3. CThey give inconsistent results
    4. DThey always have high rates of recombination when assayed with visible markers
    5. EThey are very rare
  5. 5Genetic maps
    1. ANone of the other answers
    2. BIn humans are circular, not linear
    3. CCannot be used to make predictions in pedigrees
    4. DCan be given in units of cM (centiMorgans)
    5. EHave no relationship to genetic recombination
  6. 6The Hardy-Weinberg Equilibrium always results in:
    1. AConstant gene and genotype frequencies from generation to generation
    2. B25%, 50%, and 25% as the frequencies of the three genotypes AA, Aa, and aa respectively in all cases
    3. CA tendency for the dominant allele to go towards fixation
    4. DA reduction in the frequency of heterozygotes
    5. ENone of the other answers
  7. 7Inbreeding
    1. AChanges gene frequencies quickly
    2. BResults in a stable frequency of heterozygotes
    3. CNone of the other answers
    4. DResults in the frequency of heterozygotes being halved each odd generation
    5. ECan only be done in plants, not animals
  8. 8In a certain human population, colour-blindness is 20X more frequent in males than females. This means that:
    1. A9.5% of the females are carriers of the colour-blindness gene
    2. BThe allele for colour-blindness has a frequency of 0.5
    3. CThere is selection on this characteristic
    4. DFemales can not be colourblind
    5. E0.25% of the females are not colour-blind
  9. 9When a population is small, the effect is:
    1. AHigher mutation rates
    2. BNone of the other answers
    3. CThat gene frequencies will change at random over time, and certain alleles may become fixed
    4. DHeterozygotes will steadily increase in frequency
    5. EThat recessive alleles will always disappear
  10. 10In a population mutation from the A to a allele has a frequency of 0.0001, while the reverse mutation rate is 0.0009. What is the equilibrium frequency of the a allele?
    1. A0.1
    2. BTwo of the other answers (a joke for you all – please do not choose this as the correct answer!)
    3. C0
    4. D10/11
    5. E1.0

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