Quiz
Cellular Adaptations & Necrosis
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Questions in this quiz (22)
1Which of the following is not a pattern of cell death in tissues?
- Afibrinoid necrosis
- Bfat necrosis
- Ccoagulative necrosis
- Dcontracture necrosis
2Compare acute cell injury with cellular adaptations.
- ACellular adaptations develop over a brief period of time and are reversible
- BAcute cell injury can be manifested as reversible cell swelling
- CAcute cell injury can be manifested as irreversible necrosis
3What is lipofuscin?
- ABlue-pigmented cytoplasmic inclusions in stressed cells
- BA lipid-containing residual body of autophagy
- CAn irreversible "wear and tear" pigment
- DA product of cells undergoing decreased cell turnover
4Metatstatic calcification is due to precipitation of calcium at sites of cell/tissue injury
- ATrue
- BFalse
5Which of the following mechanisms explains the pathogenesis of alcohol-induced fatty liver?
- AIncreased delivery of free fatty acids
- BIncreased lipogenesis
- CDecreased apoprotein synthesis for triglyceride export
- DIncreased utilization of triglycerides and oxidation of fatty acids
6Metaplasia can be characterized by which of the following?
- AOne adult cell type being replaced by another through chronic injury
- BIrreversible change in cells/tissue
- CDecreased risk of malignancy/neoplasia
- DIncrease in cell number
7Which is an example of physiologic apoptosis?
- AFormation of the esophageal lumen
- BSyndactyly
- CMuscular dystrophy
- DChronic lymphocytic leukemia
8Apoptosis can result from endogenous OR exogenous causes
- ATrue
- BFalse
9In a Masson Trichrome stain
- ANucleic acids stain dark blue
- BConnective tissue stains blue
- CProteins stain light purple
10Which of the following would you expect to see in necrosis?
- AA rounded up, fragmented cell morphology
- BPhagocytosis by neutrophils
- CPhagocytosis by macrophages and nonprofessional macrophages
- DFunctionally intact cell membrane
11You are examining the tissue of a patient who had a subarachnoid hemorrhage. When looking at the brain tissue microscopically, what would you expect to observe in the area of hemorrhage?
- APneumonoultramicroscopicsilicovolcanoconiosis
- BHemosiderosis
- CSteatosis
- DAnthracosis
12At what point in cell injury would you expect to observe hydropic change of the cell?
- A< 10 minutes
- B10-15 minutes
- C15-60 minutes
- D4-8 hours
13You know that irreversible cell injury is often characterized by nuclear changes. Which of the nuclear changes describes pyknosis?
- AFragmentation of the nucleus into dense basophilic fragments ("nuclear debris")
- BDissolution of nuclear fragments
- CCondensation of chromatin
- DDilation of the endoplasmic reticulum
14In coagulative necrosis, the shapes of cells and tissues change dramatically, but the nuclei/organelles are intact.
- ATrue
- BFalse
15Where would you expect to see liquefactive necrosis most often?
- ABrain
- BLungs
- CAbscesses
- DGI tract
16Your patient's cells and tissues demonstrate obvious enzymatic necrosis. You immediately know the condition that (likely) caused this is:
- ACOVID
- BAcute pancreatitis
- CMyocardial infarction
- DHypercalcemia
17What is the most common cause of caseous necrosis?
- ADry gangrene
- BWet gangrene
- CMycobacteria tuberculosis
- DEating too much cottage cheese
18Fibrinoid necrosis is caused by injury to vessel walls that causes leakage of protein and fibrin from the circulation that becomes entrapped. Which vascular injury might cause this type of necrosis?
- AImmune-complex associated vasculitis
- BAccelerated HTN
- CHTN that has slowly developed over 20 years
- DExcessive scarring
19What is a heterophagosome?
- AA secondary lysosome involved in digestion of a cell's own organelles
- BA primary lysosome fused with absorptive vesicles originating from the plasma membrane
- CA small vesicle budding from enzymes on the lateral side of the Golgi apparatus
20In your elective oncology rotation, a patient presents with multiple calcified breast tumors. You know this to be a result of metastatic calcification.
- ATrue
- BFalse
21Upon histological examination, tissue cells demonstrate what looks like "nuclear dust". This is characteristic of
- Akaryorrhexis
- Bkaryolysis
- Ckaryogram
- Dpyknosis
22In response to [blank_start]cigarette smoke[blank_end], columnar epithelial cells of the bronchial epithelium undergo squamous [blank_start]metaplasia[blank_end]. Smoking-induced metaplasia may lead to bronchial squamous cell [blank_start]neoplasia[blank_end].
- Acigarette smoke
- Bsitting for 12 hours/day
- Cdrinking too much water
- Dpulmonary HTN
- Emetaplasia
- Fhyperplasia
- Gneoplasia
Information
- Description
- Medicine Quiz on Cellular Adaptations & Necrosis, created by Trey W on 18/07/2020.
- Author
- Trey W
- Language
- English
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- 141
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