Quiz
transplant and reproductive immunology
Questions in this quiz (41)
1The graft is a graft from 1 place to another in the same individual
- Aright
- Bwrong
2Should blood group compatibility between donor and recipient be determined before kidney transplantation
- Ayes
- Bno
33. Classical MHC class II antigens (HLA-DR, DQ) have a more limited distribution than MHC class I antigens
- Ayes
- Bno
44. The most suitable cells for HLA compatibility testing are lymphocytes derived from the patient's peripheral blood
- Ayes
- Bno
5 After blood transfusions, pregnancy and previous transplants can form
circulating antibodies- Ayes
- Bno
6The acute rejection reaction of the transplanted organ is manifested:
- A3 years
- B5-6 months
- Cup to 3 months
- Dup to 1-2 weeks
7Rejection of the transplant is a manifestation of
- ACell-mediated immunity
- BAn important process in allograft rejection is humoral-mediated immunity
- CHypersensitivity of type 3 (immune complexes)
- DComplement-dependent cytotoxicity
- Ecan damage the graft through its prancreatic enzymes.
- FThe immune response to the allograft may also include antibodies- igD
8Graft reaction against the host (GVH)
- A-It manifests itself in different MHC antigens between donor and recipient
- BGVH response does require suppressor T cells
- C-May be the result of an infusion of blood products containing viable lymphocytes into
immunologically incompetent recipient - D(GVH) is caused by the destruction of cells or tissues of
immunocompetent recipient of immunocompetent stem cells
9During transplantation, the preformed cytotoxic antibodies in the recipient
- AAre responsible for the super-sharp rejection
- BCytotoxic antibodies of class IgA and IgD lead to an over-acute rejection reaction
- CCan be directed against HLA or ABO antigens of the graft
- Dall are correct
10Immunological follow-up of an organ transplant patient requires examination of
- AChanges in lymphocyte populations and subpopulations
- Bn acute rejection is dominated by CD3 + T lymphocytes
- CDonor-specific AT
- DSerum levels of cytokines
- Eserum levels of interferons
11In recipients with repeated kidney transplants, graft survival compared to
that in recipients with a first kidney transplant is:- Areduced
- Bincreased
- Crecurrent antigenic incompatibilities (especially DR) between donor and recipient in repeated kidney transplants have a positive effect on graft survival.
12Prevention of hemolytic disease of the newborn due to compatibility with maternal Rhesus (RhD) factor includes
- Apassive maternal immunization to remove Rh antigen
- Bactive maternal immunization to remove Rh antigen
- Cinfusion done after 72hours after the first birth
- Dinfusion of anti-RhD antibodies to the Rh (+) mother
13If the mother develops IgG AT to A and B erythrocyte antigens of the fetus, hemolytic disease of the newborn will appear in children from:
- A- 0 mother and AB father
- BAB mother and 0 father
- CA mother and ab father
- D0 mother and A father
14Which of the following AGs are rich in cell membranes of B-lymphocytes
- AMHC class II antigens
- BMHC class I antigens
- Call are correct
- Dnone are correct
15Class III MHC regions in the major human tissue compatibility complex contain genes which encode
- A- components of the complement system
- Bheat shock proteins and cytokines
- Cnone are correct
- Dcomponents of cellular immunity
16 Antimetabolites that suppress the immune response are the purine antagonists are
- Ainvolved in dna synthesis
- Bmercapturin
- Cazathioprine
- Dinvolved in mRna synthesis
17Hypersensitivity graft rejection is associated with
- Apreformed cytotoxic
antibodies - Bcomplement activation
- Ccellular immunity
- Dnantural resistance
- Apreformed cytotoxic
18The accelerated rejection reaction involves the following immunological factors and
mechanisms of- Asensitized T cells preformed by HLA AT formed during immune response to graft or AZKC
- Bactivated b cells
- Ccomplement system
- Dall are correct
19Molecular genetic methods for HLA typing in clinical transplant practice
include- Aelisa
- Belectrophoresis
- Cimmunoblot
- Dpcr
20The cells infiltrating the graft in the acute rejection reaction are predominantly
- ACD4 +
- BCD3 +
- CCD16 +
- DCD8+
21 Allogeneic transplantation
- Abone marrow transplantation from mother to daughter
- Bbone marrow transplantation from daughter to mother
- Cbone marrow transplantation from mother to son
- Dbone marrow transplantation from father to daughter
22Autologous transplantation
- Atransplantation of skin from the thigh to the face of the same individual
- Btransplantation of skin from the thigh to the face of the different individual
- Ctransplantation of skin from the thigh of a twin to the face of the other twin individual
- Ddone to replace cicatrix for cosmetic procedure
23Syngenna
- Abone marrow transplantation from same individual
- Bbone marrow transplantation between twins
- Cbone marrow transplantation between family members
- Dbone marrow transplantation between two compatible donor and recipient
24Sources of stem cells
- Aserum
- Bperipheral blood
- Cpancreas
- Dumbilical cord
- Ebone marrow
- Fepiphysis
25Gene loci of the HLA-class II region (3 correct)
- Adp
- Brt
- Cdq
- Ddr
- Eds
- Flocated in the long arm of the
sixth chromosome in humans
26 Hormones: luteinizing (LH), follicle-stimulating (FSH), inhibin B and estradiol, are tested in serum to assess ovarian reserve in women with reproductive disorders
- Ayes
- Bno
27 Recurrent abortions are not associated with defects in coagulation factors or circulating anticoagulants (lupus-like anticoagulants)
- Acorrect
- Bincorrect
28 Women with positive anti-ovarian antibodies have an increased chance of becoming pregnant
after birth control in vitro fertilization or embryo transfer compared to women in whom no such was found antibodies- Ano
- Byes
29 Antibodies in women with reproductive disorders are tested by serum
- Ayes
- Bno
30Antiphospholipid syndrome is associated with the presence of anticardiolipin antibodies, loss of
fetal, arterial and venous thrombosis- Ano
- Byes
31which hormone is secreted by the granulosa cells of the ovary and controls the series of
follicle-stimulating hormone from the pituitary gland- Afsh
- Blh
- Cinhibin b
- Destradiol
32Which immune indicators are associated with premature decline in ovarian function
- Arbc,wbc,anti-dna
- Bca19-9, anti phospholipid,antithyroid
- C- antiphospholipid, antinuclear, antithyroid and anti-ovarian AT
- Dnone of the above
33The study of the reproductive immunophenotype in women with reproductive problems includes
- AT-lymphocytes CD3 +, CD4 +, CD8 +
- BB-lymphocytes CD19 +
- CNK cells CD3 CD56 +, CD16 +
34 Immunological manifestations in patients with endometriosis and reproductive problems are
demonstrated- Aincreased serum levels of antiphospholipid and antinuclear antibodies
- Bactivated reproductive phenotype and increased NK-cell cytotoxicity
- Cincrease in CA125
35In patients with previous abortions, monitoring and prognosis of the current
pregnancy includes a study of serum concentrations of- AFSH
- B- beta human chorionic gonadotropin
- CLH
- Dpituitary gland
36 HLA-G antigens are expressed in
- Amyoblast
- Bosteoblasts
- Ctrophoblasts
- Dlymphokines
37The main functions of HLA-G antigens are (SPECIFY THE WRONG ANSWER)
- Ainhibiting the antitrophoblast activity of maternal NK cells
- Bprotecting the fetus from the mother's immune response against the paternal antigens in it
- Cinducing frequent abortions
- Dprotection of the fetus from transplant infections
38 Elevated NK cells in women with frequent abortions (SPECIFY THE WRONG ANSWER)
- Asecrete tumor necrosis factor (TNF)
- Bare examined by peripheral venous blood in an anticoagulant
- Care cytotoxic to the placental trophoblast
- Dthey don't matter
39The immunological examination of anti-phospholipid syndrome in pregnant women includes
- A- anticardiolipin antibodies
- B-antibodies to phosphatidylethanolamine, phosphatidylinositol, phosphatidic acid, phosphatidylglycerol, phosphatidylserine, phosphatidylcholine
- Canti-beta-2-glycoprotein I AT
40Anti-ovarian antibodies include AT versus (2 correct)
- Aantigens of the pellucid zone
- Bantigens of steroid-producing granulosa-luteinizing cells
- CAntibodies against the pellucid zone are also important in specifying
cases of cervical cancer - DAntibodies against the pellucid zone are also important in specifying
cases of cystic disease.
41The normal development of pregnancy is due to the predominance of
- ATh1 cytokines
- BTh2 cytokines
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- Medicine Quiz on transplant and reproductive immunology, created by mariam Butt on 07/07/2021.
- Author
- mariam Butt
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- English
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