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The Anatomy and Function of a Myofibril, Myofilaments, Actin, Myosin other proteins

Vincent Conquer 12 questions

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  1. 1What is a myofibril?
    1. Athe muscle fiber
    2. Bthe actin filament
    3. Cthe myosin filament
    4. Dcolumnar protein columns alongside the muscle fiber
  2. 2Bodily movements or motion occur when muscles contract or shorten. Which of the following best describes how this occurs?
    1. Akk
    2. BActin, when polymerized into filaments, forms the "ladder" along which the myosin filaments "climb" to generate motion.
  3. 3Six different proteins and molecules participate in the contraction of a sarcomere, namely:
    myosin
    actin
    tropomyosin
    troponin
    ATP
    Ca2+ ions
     
    Some of these combine together to form thick and thin filaments.


    Read more: http://slidingfilament.webnode.com/sliding-filament-theory/
    1. Akk
    2. Bjj
  4. 4a) Thick filaments - The thick filament is composed of myosin. The projections from the myosin filament are called crossbridges. The crossbridge is believed to be a molecular motor that converts chemical energy into mechanical work.

    b) Thin filaments - The thin filament is composed of actin, troponin, and tropomyosin.
    1. Ak
    2. Bo
  5. 5Regulatory proteins are :
    1. Amyosin is a contractile filament

      titin and nebulin are structural proteins

      contractile protein , Actin
      -consists of 2 alpha helical strands of g-actin molecules bonded in series
      -each g-actin has a binding site where the s1 fragment of the myosin cross-bridge complex binds during muscle contraction


      -contractile protein, myosin
      -consists of two heavy (form tail region and two cross-bridges that bind with actin to produce force) and four light chains (that influence cross-bridge cycling kinetics and therefore sarcomere contraction velocity

      -contractile protein
      -consists of two heavy (form tail region and two cross-bridges that bind with actin to produce force) and four light chains (that influence cross-bridge cycling kinetics and therefore sarcomere contraction velocity


      Muscle contractile protein
      Heart and muscle contractile fibres consist of bundles of actin polymers that slide alongside each other by the activity of the motor protein myosin and associated contractile proteins such as troponin and titin

      Muscle contractile protein
      Heart and muscle contractile fibres consist of bundles of actin polymers that slide alongside each other by the activity of the motor protein myosin and associated contractile proteins such as troponin and titin

      regulatory proteins
      proteins that help turn the muscle contraction process on and off

      contractile proteins
      proteins that produce force during muscle contraction

      structural proteins
      proteins that connect the outer layer of myofibrils to the sarcolemma, keep the actin and myosin filaments in proper alignment, and give the myofibrils their elasticity and extensibility

      tropomyosin
      -two per actin filament
      -when muscle is relaxed, covers the myosin-head binding sites on the actin filament

      troponin
      -binds to both actin and tropomyosin
      -has binding site for Ca+2 needed for muscle contraction
      -located at the junction of each successive pair of tropomyosin molecules

      titin
      -stabilizes the alignment of the thick filaments by connecting each myosin filament to both the z line and the m line
      -the titin that extends from the z line to the beginning of the myosin filament is believed to help keep the myosin filaments centered between the z lines
      -helps the sarcomere return to its resting length after the muscle has contracted or been stretched, contributing to the myofibril's elasticity and extensibility

      nebulin
      -extends the length of each actin filament
      -believed to anchor the actin filament to the z-line and help regulate the length of the actin filament

      actin
      -contractile protein
      -consists of 2 alpha helical strands of g-actin molecules bonded in series
      -each g-actin has a binding site where the s1 fragment of the myosin cross-bridge complex binds during muscle contraction


      myosin
      -contractile protein
      -consists of two heavy (form tail region and two cross-bridges that bind with actin to produce force) and four light chains (that influence cross-bridge cycling kinetics and therefore sarcomere contraction velocity
    2. Bproteins that help turn the muscle contraction process on and off
    3. Cproteins that regulate bodily systems and are used in homeostasis
  6. 6Titin and nebulin are structural proteins


    1. ATrue
    2. BFalse
  7. 7actin
    - is a contractile protein
    -consists of 2 alpha helical strands of g-actin molecules bonded in series
    -each g-actin has a binding site where the s1 fragment of the myosin cross-bridge complex binds during muscle contraction


    1. ATrue
    2. BFalse
  8. 8 myosin
    1. A-is a contractile protein
    2. B-consists of two heavy (form tail region and two cross-bridges that bind with actin to produce force) and four light chains (that influence cross-bridge cycling kinetics and therefore sarcomere contraction velocity
    3. Cis a myofilament , a filament of a myofibril
    4. DAll of these are true
  9. 9contractile proteins


    1. Aproteins that produce force during muscle contraction
    2. Bproteins that bind with troponin
    3. Care centered with the M-line
    4. Dproteins that build muscle
  10. 10structural proteins:
    proteins that connect the outer layer of myofibrils to the sarcolemma, keep the actin and myosin filaments in proper alignment, and give the myofibrils their elasticity and extensibility
    1. ATrue
    2. BFalse

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The Anatomy and Function of a Myofibril
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