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Cell Signalling - test 1
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Questions in this quiz (17)
1integrator proteins
- Aintegrate signals from different pathways
- Bwork as part of intracellular signalling pathways
- Chelp integrate signals before relaying the signals forward
- Dall of the above
- Eabstain
2what is the purpose of having multiple steps in any intracellular signalling pathway?
- Amultiple opportunities for signal modulation
- Baugmentation of the signal (divergence)
- Copportunities for pathway integration
- Dall of the above
- Eabstain
3receptors are classified according to...
- Atheir ligands
- Btheir effects
- Ctheir structure
- Dtheir abundance in the body
- Eabstain
4which of the following concerning steroid hormones is FALSE?
- Athey are hydrophobic
- Bthey bind to intracellular receptors
- Cthey usually bind G-protein coupled gene regulatory proteins
- Dtestosterone is a steroid hormone
- Eabstain
5which of the following is NOT one of the 3 main domains of a nuclear receptor?
- ADNA binding domain
- Btranslation activating domain
- Cligand binding domain
- Dall of the above are nuclear receptor binding domains
- Eabstain
6ionotropic receptors (ion channel linked receptors) are NOT gated by...
- Aintracellular/ extracellular ligands
- Bchanges in membrane voltage
- Cchanges in membrane permeability
- Dmechanical stretch
- Eabstain
7Concerning ion channel linked (inotropic) receptors, which of the following is TRUE?
- AThey are only gated by changes in intracellular/ extracellular ligands or changes in mechanical stretches
- Bone receptor is usually assembled on a single polypeptide chain
- Cin the resting state channels are always closed
- Dions pass through the channel down the concentration gradient
- Eabstain
8GPCRS have how many membrane spanning domains?
- A3
- B5
- C7
- D9
- Eabstain
9which of the following is NOT something that a GPCR may affect?
- Asleep regulation
- Bblood pressure regulation
- Cinsulin secretion
- Dperception of pain
- Eabstain
10concerning GPCRs, which of the following is TRUE?
- Athey have no ion pore or enzymic activity
- Bthey have 5 transmembrane domains
- Cthey are named after the end product that their respective signalling pathway produces
- Dthey are the second most abundant cell surface receptor, behind ionotropic receptors
- Eabstain
11approx. what percentage of drugs target GPCRs?
- A25%
- B30%
- C50%
- D80%
- Eabstain
12GTP is converted to GDP by...
- Ahydrolysis
- Bcarboxylation
- Coxidation
- Dreduction
- Eabstain
13which subunit of the GPCR has intrinsic GTPase activity?
- Aa subunit
- BB subunit
- Cy subunit
- Dall subunits aforementioned
- Eabstain
14which subunits of the GPCR target ligand gated ion channels downstream?
- Ab and y subunits
- Ba subunits
- Cb subunits
- Dall subunits
- Eabstain
15which G protein stimulates phospholipase?
- AGo
- BGq
- CGs
- DGi
- Eabstain
16adenylyl cyclase regulates the production of ....
- AcGMP
- BcAMP
- CcATP
- DcGTP
- Eabstain
17concerning PKA (protein kinase A), which of the following is FALSE?
- Ait works fast in muscle cells
- Bit works slowly in gene transcription
- Cits signals can be terminated by protein phosphates
- Dit is rapidly destroyed by cATP phosphodiesterases
- Eabstain
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- Description
- Quiz on Cell Signalling - test 1, created by stephiesteph01 on 06/06/2014.
- Author
- stephiesteph01
- Language
- English
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