Lung Cancer

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USMLE Step 2 Pulmonology (2b Lung Neoplasms) Flashcards on Lung Cancer, created by Aaron Samide on 23/05/2016.
Aaron Samide
Flashcards by Aaron Samide, updated more than 1 year ago
Aaron Samide
Created by Aaron Samide almost 8 years ago
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Question Answer
What percentages of lung cancers are small cell vs. non-small cell? 25% small cell 75% non-small cell
Jobs in which exposure to asbestos is common (4) - Shipbuilding - Construction - Car mechanics - Painters
High levels of radon are found in _________. Basements
Staging of NSCLC vs SCLC NSCLC = TNM system SCLC = limited vs. extensive (limited = chest + supraclavicular nodes; extensive = outside of that area)
Superior vena cava (SVC) syndrome most commonly occurs with what type of lung cancer? Small cell (occurs in 5% of cases)
Findings in SVC syndrome - Facial fullness - Facial & arm edema - Dilated veins over anterior chest, arms, face - JVD
Why do 1% of lung cancer patients get hemidiaphragmatic paralysis? Tumor destruction of phrenic nerve
Why do 3% of lung cancer patients have hoarseness? Recurrent laryngeal nerve palsy
Horner syndrome triad Miosis Ptosis Anhidrosis
Pancoast tumors are usually associated with what lung cancer type? Squamous cell
Findings associated with Pancoast tumors Superior sulcus mass involving C8 and T1-T2 nerve roots --> shoulder pain radiating down arm, upper extremity weakness, Horner syndrome
Prognosis if malignant pleural effusion is present Very poor -- equivalent to distant mets
Types of lung cancer associated with hypertrophic pulmonary osteoarthropathy Adenocarcinoma Squamous cell
Lambert-Eaton syndrome is most common in which type of lung cancer? Small cell
Stability of a CXR abnormality over a _________ period is almost always associated with a benign lesion 2-year
T/F: Lung cancer can be diagnosed by CXR and CT alone. False; pathologic confirmation is necessary regardless of CXR and CT results.
5-year survival for SCLC if disease is limited vs. extensive Limited: 10-13% Extensive: 1-2%
Overall 5-year survival for lung cancer patients 14%
NSCLC treatment options Surgery = best option (patients with mets outside the chest are NOT candidates) Radiation = important adjunct
Limited SCLC treatment options Combo of chemo and radiation
Extensive SCLC treatment options Chemo alone initially If patient responds, use prophylactic radiation to decrease incidence of brain mets and prolong survival
Role of surgery in SCLC Limited; most of these tumors are non-resectable
T/F: Most asymptomatic lung masses are benign. True
Which types of lung cancer are usually central, and which are usually peripheral? Central - squamous cell, small cell Peripheral - adenocarcinoma, large cell
Cavitation on CXR is associated with what type of lung cancer? Squamous cell
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