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1046639
CANCER BRONCOPULMONAR.
Description
Mind Map on CANCER BRONCOPULMONAR., created by edgar_chavez28 on 01/07/2014.
Mind Map by
edgar_chavez28
, updated more than 1 year ago
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Created by
edgar_chavez28
almost 10 years ago
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Resource summary
CANCER BRONCOPULMONAR.
FISIOPATOLOGIA / ETIOLOGIA
GENETICO
GENES: p53, Kras, myc, c-erb-B1
FACTORES MODIFICABLES
Indice Tabaquico: (#cigarrillos al dia x años fumando) / 20. > 20 paqs/año; 22 veces mas el riesgo.
Otras sustancias: Asbesto, arsénico, Niquel, radón)
SINTOMATOLOGIA.
Asintomático: 5-12%
TOS 90%
Expectoración 70%
Hemoptisis 20%
Dolor Torácico 30%
Perdida de peso 60%
DIAGNOSTICO
HISTOLOGIA.-...Biopsia Bronquial (CA CENTRAL), Biopsia Transbronquial (CA PERIFERICO):
CLASIFICACION
CA. CEL PEQUEÑAS...15%
Localización....CENTRAL
Origen...Cels. KULTSCHITZKY
Productor...Granulos neurosecretores
1° Causa de Sd Paraneoplásicos
1° Causa de SVCS
1° Causa de METS
TIPOS: 1)Cels Avena, 2) Poligonal, 3) Linfocitico, 4) Fusiforme
Hueso (40%), Higado (34%), Cerebro (14%), Nodulos (25%)
Cushing (++ ACTH), ++HAD, ++Ca (++PARATIROIDE), etc
PEOR PRONÓSTICO
CA. CELULAS NO PEQUEÑAS
ADENOCARCINOMA....50%
Localización......PERIFERICA
Origen.....Gls Mucosas
Productor....MUCINA
Crea....1° DERRAME PLEURAL
TIPOS: 1)Bronquioalveolar, 2) Acinar, 3) Papilar, 4) Sólido
Asociación.....1° CIGARRO
CA. EPIDERMOIDE.....25%
Localización....CENTRAL
Crea...1° ATELECTASIAS...1° TUMOR DE PANCOAST....1° CAVIDADES X NECROSIS ISQUEMICA (HEMOPTISIS)
Tipos...Escamoso, espino-celular
CA CEL. GRANDES.....10%
Localización...PERIFERICO
METS muy lentamente
ESTADIFICACIÓN Y TRATAMIENTO
MICROCITICO:
DISEMINADO: Más frecuente y NO tolera Radioterapia.
LOCALIZADO: 1 Hemitorax, ganglios regionales (campo tolerable de radioterapia torácica).
CA. NO MICROCITICO...TNM
Estadios pecoces (IA, IB, IIA): Cirugía y radioterapia
Estadios avanzados (IIIB, IV): Radioterapia y quimioterapia (paliación)
Media attachments
CA_MICROCITICO (image/jpg)
ADENOCARCINOME_PULMON (image/jpg)
Sd_Pancoast (image/jpg)
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