Tuberculosis

Description

Mind Map on Tuberculosis, created by Fatima Alkhateeb on 03/02/2019.
Fatima Alkhateeb
Mind Map by Fatima Alkhateeb, updated more than 1 year ago
Fatima Alkhateeb
Created by Fatima Alkhateeb about 5 years ago
176
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Resource summary

Tuberculosis
  1. Anatomy
    1. Risk factors
      1. Close contact
        1. Immigration from endemic area
          1. Children less than 5 years
            1. Diabetes
              1. Malnourished people
              2. Stages
                1. Primary
                  1. Mostly asymptomatic, some have flu-like symptoms
                    1. Cell mediated immunity (3 weeks)
                      1. Ghon complex (gown focus + lymph node)
                      2. Secondary
                        1. Reactivation of dormant TB
                        2. Systemic military TB
                          1. Kidneys (sterile pyuria, WBC in the urine)
                            1. Meningitis
                              1. Pott's disease (lumbar vertebra)
                                1. Addison's disease (adrenal glands)
                                  1. Hepatits (liver)
                                    1. Lymphadenitis in the neck (scrofula)
                                  2. Radiology
                                    1. Tree in a bud
                                    2. Treatment and management
                                      1. 4 drugs for 2 months, 2 drugs for 4 months
                                        1. Rifampin (inhibits RNA synthesis)
                                          1. Isoniazid (inhibits cell wall synthesis
                                            1. Pyrazinamide (unclear exact target)
                                              1. Ethambutol (inhibits cell wall synthesis
                                                1. Optic neuropathy as an adverse effect
                                            2. Prognosis
                                              1. patients with treated TB can expect to do well with minimal or no sequele
                                                1. Poor : in anemic states, smokers, late presentation of the disease
                                                2. Signs&symptoms
                                                  1. Cough
                                                    1. Mechanism
                                                      1. Stimulation of mechano-or chemoreceptors
                                                        1. Afferent impulses to cough center (medulla)
                                                          1. Efferent impulses via vagus, phrenic, intercostal nerves
                                                            1. Increased contraction of muscles --> noisy expiration (cough)
                                                      2. Types
                                                        1. Productive
                                                          1. presence of excessive sputum, expectorants are useful
                                                            1. Sputum color
                                                              1. Mucoid (clear and white)
                                                                1. normally of little consequence and suggest that no infection is there
                                                                2. Yellow, green or brown
                                                                  1. indicates infection, probably caused by a bacterial infection, such as bronchitis or pneumonia
                                                                  2. Hemoptysis
                                                                    1. Blood in the sputum, rusted (pneumonia), pink but thin and frothy (LVF), dark red (carcinoma)
                                                              2. Non-productive
                                                                1. serving no useful purpose, increased discomfort to the patient
                                                            2. Clubbing
                                                              1. Other Causes
                                                                1. Cyanotic heart diseases
                                                                  1. Cystic fibrosis
                                                                    1. Lung cancer
                                                                      1. Ulcerative colitis
                                                                        1. Lung abscess
                                                                          1. Infective endocarditis
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