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Insulin resistance/ Metabolic syndrome

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Mind map of insulin resistance
rebeccasteele96
Mind Map by rebeccasteele96, updated more than 1 year ago
rebeccasteele96
Created by rebeccasteele96 about 9 years ago
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Resource summary

Insulin resistance/ Metabolic syndrome
  1. dysregulation of insulin & glucose metabolism
    1. Symptoms
      1. hyperkeratosis skin conditions
        1. type 2 diabetes
          2. High blood pressuer
            1. acne vulgaris
            2. Causes
              1. refined CHO
                1. Increased Blood Sugar
                  1. GL = GI of food x CHO per serving
                    1. Higher GL= Higher Blood sugar=higher release of insulin
                      1. HEALTHY person= rapid uptake of glucose in peripheral cells (blood cells)
                        1. GI measure rise in blood sugar after eatinga specific food.
                      2. reduce blood sugar
                        1. add protein
                          1. Lower GL Foods
                        2. reduction in sensitivity of insulin receptors - hyperinsulinaemia
                        3. lack of exercise
                      3. insulin receptor resistance
                        1. TYPE 1 -insulin deficiency
                        2. Decrease in sensitivity of body tissues to the action of insulin
                          1. chronic elevation of blood glucose
                            1. Insulin
                              1. VLDL
                                1. Free fatty acids - inhibit insulin uptake
                                  1. Dyslipidaemia
                                    1. glucgon activates hormone sensitive lipase - stimulates Free fatty acids into blood stream
                                      1. the liver - glucagon stimulates triglycerides synthesis - so cholestorol, shifts from HDL to VLDL
                            2. biochemical changes
                              1. pancreatic beta cell release more insulin
                              2. resistant tissue
                                1. adipose
                                  1. Liver
                                    1. Skeletal muscle
                                      1. < in glucose in muscle cells, increases conversion of amino acids, = >glucose. ^alamine levels & pancreatic cells produce glucogen - action on liver cells stimulating glycolysis &glucogenesis >more glucose released
                                        1. TYPE 2 DIABETEs
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