Quiz
PHSI3011 12-1 Comparative Physiology and Thermal #1
Questions in this quiz (17)
1GnIH means what?
- AGonadotropin Inducing Hormone
- BGonadotropin Inhibitory Hormone
2Gonadotropin Inhibitory Hormone (GnIH) first discovered in 2000 in what model?
- ABirds
- BMice
- CFish
- DSalamanders
3What does GnIH appear to be the “signaller” for in humans?
- AStress-related suppression of reproduction
- BMenopause
- CPuberty
- DPregnancy-induced placentation changes
4GnIH is also called:
- ARFamide-Related Peptide-3
- BFRamide-Related Peptide-3
- CRFamide-Related Peptide-1
- DFRamide-Related Peptide-1
5True or false: GnIH has been found within the NERVOUS SYSTEMS of animals with all major phyla.
- ATrue
- BFalse
6GnIH is:
- AUsually released into the portal system, but not in some animals (rats, mice).
- BReleased into the portal system, but only in some animals (rats, mice).
7A major similarity between organisms is that GnIH is always localised in the:
- ADorsomedial nucleus of the hypothalamus
- BDorsomedial nucleus of the hippocampus
- CDorsal horn of the hypothalamus
- DDorsal horn of the hippocampus
8True or false: A major similarity between organisms is that GnIH neurons project to GnRH cells in all mammalian species studied.
- ATrue
- BFalse
9True or false: A major similarity between organisms is that GnIH neurons project into the neurosecretory zone of the median eminence in all mammalian species studied.
- ATrue
- BFalse
10Advantages of using LAB AND DOMESTICATED animals as models include:
(select all that apply)- AWell-adapted to labs
- BDetailed knowledge of genetic background
- CTransgenic manipulation allows specific focus
- DShort generation time (longitudinal studies simple and comprehensive)
11An example of a “Wild” species used as a model is the Tree shrew. What is it used to model?
- APTSD
- BAlzheimer’s
- CCystic Fibrosis
- DDevelopmental disorders
12Alzheimer’s Disease (AD) is characterised by progressive loss of cholinergic neurons projecting from the basal forebrain to which areas:
(select all that apply)- ACortical
- BHippocampal
- CHypothalamic
13The two main histopathological hallmarks of Alzheimer’s Disease (AD) are:
(select the two that apply)- AExtracellular senile plaques containing amyloid-beta (Aβ) which is formed after sequential cleavage of Amyloid Precursor Protein (APP) by the catalytic activity of β-secretases and γ-secretases
- BIntracellular Neurofibrillary Tangles (NFTs)
14True or false: A disadvantage of using transgenic models of AD is that many are “icon” species and therefore politically unsuitable.
- ATrue
- BFalse
15Which of the following wild animals could be candidates as AD models? (but aren’t because of reasons)
(select all that apply)- AWolverines
- BDolphins
- CPolar Bears
- DTasmanian Tigers
- ETasmanian Devils
16The best [non-transgenic, anyway] model for Alzheimer's Disease (AD) is the:
- ADegu (Octodon degus)
- BGuinea pig (Cavia porcellus)
- CNaked mole-rat (Heterocephalus glaber)
- DDomestic dog (Canis familiaris)
- EFat-tailed dunnart (Sminthopsis crassicaudata)
17What age do Degus start presenting Alzheimer’s symptoms?
- A~3-4 years
- B~4-5 years
- C~5-6 years
- D~6-7 years
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- PHSI3011 12-1 Comparative physiology and thermal physiology #1
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- English
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- Created on 5 Nov 2017 · updated on 10 Nov 2017
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