GoConqr has a new look! Let us know what you think.

Sign up free

Quiz

PHSI3012 02-2 Limitless replicative potential of cancer cells

Deleted user 11 questions Updated 18 Nov 2017

Take the quiz

This quiz has question types that open in the usual player.

Questions in this quiz (11)

  1. 1True or false:
    Cells which have entered senescence have a large, flattened morphology "like poached eggs".
    1. ATrue
    2. BFalse
  2. 2Mutations in p53 and/or Rb can lead to:
    1. ABypassing senescence and crisis.
    2. BBypassing senescence and entering crisis.
    3. CEntering crisis.
    4. D[none of the above]
  3. 3Cells in "crisis" have which of the following traits?
    (select all that apply)
    1. AMassive cell death
    2. BReduced cell death
    3. CIncreased genomic stability
    4. DGenomic instability
  4. 4The Hayflick limit is:
    1. AThe number of divisions a cell can undergo before entering senescence.
    2. B(not this one)
  5. 5Telomeres shorten by ~[blank_start]_____[blank_end] bp with each round of cell division.
    1. A5 - 15
    2. B50 - 150
    3. C500 - 1,500
    4. D5,000 - 15,000
    5. E130 - 210
    6. F2,000 - 40,000
  6. 6There are two [main?] telomere maintenance mechanisms. These are Telomerase and ALT.
    What does ALT stand for?
    [blank_start]_____[blank_end]
    1. AAlternative Lengthening of Telomeres
  7. 7Which [non-cancerous] cell type does NOT have shortening telomeres during replication?
    1. AGerm line cells
    2. BStem cells
    3. CCardiomyocytes
  8. 8Telomerase is:
    1. AAn enzyme
    2. BA protein
    3. CA molecule
  9. 9Which telomere maintenance mechanism is used in the majority of cancers?
    1. ATelomerase
    2. BALT
  10. 10Telomerase can be detected using which of the following methods:
    (select all that apply)
    1. ATRAP (Telomere Repeat Amplification Protocol) assay
    2. BTRF (Terminal Restriction Fragment) assay
    3. CAPBs (ALT-associated PML Bodies)
    4. DC-circle assay
    5. EMovement of the telomere tag

Information

Description
PHSI3012 02-2 Limitless replicative potential of cancer cells Content: * Hallmarks of Cancer * Cellular proliferation * Mortality vs immortality * Telomeres * Telomerase * ALT
Author
Deleted user
Language
English
Views
25
History
Created on 18 Nov 2017 · updated on 18 Nov 2017
Rating
No ratings yet
Rate this quiz
Rate this quiz

Feedback

What is it about?

What do you think of the new look?

How do you like it?