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Lecture 7 Strep
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Questions in this quiz (22)
1What is the mode of transmission for Streptococcus pyogenes?
- APerson --> person by direct contact (mucosa or secretions), Contaminated droplets
- BFetal and Infant infections: from mother (in utero or during delivery)
- C person-to-person, directly or via medical equipment --> nosocomial spread
- APerson --> person by direct contact (mucosa or secretions), Contaminated droplets
2Where is Streptococcus pyogenes habitat?
- ANormal flora of female genital tract & of lower GI tract, occasional colonization of upper respiratory tract
- BSkin & upper respiratory tract (humans)
- CNasopharynx (humans)
- DNormal flora of oral cavity (humans)
- ESoil, food, water, Normal flora of humans, animals, birds, E. feacium & E. feacalis normal flora of human GI tract & female GU tract
- FGI tract flora
- ANormal flora of female genital tract & of lower GI tract, occasional colonization of upper respiratory tract
3Which of the following streps can cause these infections;
Strep Throat
#1 cause of pharyngitis
Pain, fever, headache
Throat swab --> test for S.
Scarlet Fever:
complication following Strep throat
rash desquamation
Mainly children
Rheumatic fever:
Serious complication following Strep throat
Fever, inflammation of the heart and joints
Cross-reactions of Abs against strep Ags with heart tissue tissue damage- AViridans Streptococci
- BEnterococcus sp.
- CStreptococcus pyogenes
- DStreptococcus pneumonia
4Which of the following can cause these infections;
- Impetigo
vesicles --> pustule --> rupture --> “crust”
young children
Staph aureus often also involved
- Erysipelas
small red lesion expands
internal spread via lymph
serious complications:
Endocarditis
Pneumonia- AStrep Anginosus
- BStrep bovis
- CStreptococcus agalactiae
- DStreptococcus pyogenes
5Which of the following can cause Severe Invasive Streptococcal Infections: Streptococcal Toxic Shock Syndrome (STSS)
- Starts with localized pain & inflammation
Nonspecific symptoms:
Fever, chills, nausea, vomiting, diarrhea
Rapid onset of Shock & multiorgan failure
Drop in blood pressure
Risk groups:
HIV+, Cancer, diabetics, iv drug users- AViridans Streptococci
- BEnterococcus sp.
- CStreptococcus pyogenes
- DStrep bovis
6Which of the following can cause Severe Invasive Streptococcal Infections Necrotizing Fasciitis
- “Flesh-Eating Disease”
entry through break in skin soft tissue infection
cellulitis is 1st stage:
attacks subcutaneous & deeper tissues
RAPID spread necrosis
muscle & fat destruction
STSS often associated shock, multi-organ system failure
Treatment?
IV antibiotics & surgical debridement- AStreptococcus agalactiae
- BStreptococcus pneumonia
- CStrep bovis
- DStreptococcus pyogenes
- EEnterococcus sp.
7Which of the following fits this description;
- GPC
- Beta-hemolytic, grey and translucent
Catalase negative
- Lancefield grouping “A”
- PYR- positive
- Bacitracin- sensitive (presumptive)- AStreptococcus agalactiae
- BStreptococcus pyogenes
- CStrep bovis
- DViridans Streptococci
8Where is streptococcus agalactiae habitat?
- ANormal flora of female genital tract & of lower GI tract, occasional colonization of upper respiratory tract
- BSkin & upper respiratory tract (humans)
- CNasopharynx (humans)
- DNormal flora of oral cavity (humans)
- ESoil, food, water, Normal flora of humans, animals, birds, E. feacium & E. feacalis normal flora of human GI tract & female GU tract
9Which of the following has a mode of transmission in which Fetal and Infant infections: from mother (in utero or during delivery)
- AViridans Streptococci
- BEnterococcus sp.
- CStreptococcus agalactiae
- DStrep Anginosus
- EStrep bovis
10Which strept is responsible for Neonatal disease
1-2 infants per 1000 births
Early onset disease
Hrs—7 days after delivery
Meningitis & bacteremia
Prevention: screening and prophylaxis during pregnancy (penicillin)
Adults & older children:
UTIs, pneumonia, meningitis
Virulence Factors
Capsule --> antiphagocytic- AViridans Streptococci
- BStreptococcus pyogenes
- CStreptococcus agalactiae
- DStreptococcus pneumonia
11Which one of the following fits this description?
- GPC
- Beta-hemolytic, grey and translucent
- Catalase negative
- Lancefield grouping “B”
- CAMP test positive- AStreptococcus pyogenes
- BStreptococcus agalactiae
- CStrep bovis
- DStrep Anginosus
- EEnterococcus sp.
12Where does Streptococcus pneumoniae habitat?
- ANormal flora of female genital tract & of lower GI tract, occasional colonization of upper respiratory tract
- BSkin & upper respiratory tract (humans)
- CNasopharynx (humans)
- DGI tract flora
- ESoil, food, water, Normal flora of humans, animals, birds, E. feacium & E. feacalis normal flora of human GI tract & female GU tract
13Which one of the following has a mode of transmission
Person --> person by contact with respiratory secretions
Aspiration into lungs --> pneumonia- AStreptococcus agalactiae
- BStreptococcus pneumonia
- CStrep Anginosus
- DViridans Streptococci
- EEnterococcus sp.
14Which one of the following causes Disease
- Pneumonia
- Meningitis
- Sinusitis, otitis media
Virulence Factors:
Polysaccharide capsule (antiphagocytic)
Pneumolysin --> host cell- AStreptococcus pyogenes
- BStreptococcus pneumonia
- CStrep bovis
15Which one of the following fits this description?
- GPC- pairs lancet shaped
- Alpha-hemolytic, grey and translucent (may be mucoid) checker piece
- Fastidious-requires BAP and CO2
- Catalase negative
- Optochin sensitive
- Bile soluble- AStreptococcus pyogenes
- BStrep Anginosus
- CStrep bovis
- DEnterococcus sp.
- EStreptococcus pneumonia
16Where does viridans streptococci habitat?
- ANormal flora of female genital tract & of lower GI tract, occasional colonization of upper respiratory tract
- BNasopharynx (humans)
- CNormal flora of oral cavity (humans)
- DSkin & upper respiratory tract (humans)
- ESoil, food, water, Normal flora of humans, animals, birds, E. feacium & E. feacalis normal flora of human GI tract & female GU tract
17Which strept has a mode of transmission listed;
- Opportunistic only
- Endogenous strains --> only a pathogen if isolated in sterile sites
- Sub-acute endocarditis
- Bacteremia & other infections in immunocompromised patients
- Dental caries (S. mutans)
- Virulence Factors: Low virulence!- AViridans Streptococci
- BStreptococcus agalactiae
- CStrep Anginosus
- DStrep bovis
- EStreptococcus pyogenes
18Where does Enterococcus sp. habitat?
- ANormal flora of female genital tract & of lower GI tract, occasional colonization of upper respiratory tract
- BSkin & upper respiratory tract (humans)
- CNasopharynx (humans)
- DGI tract flora
- ESoil, food, water, Normal flora of humans, animals, birds, E. feacium & E. feacalis normal flora of human GI tract & female GU tract
19What has a mode of transmission;
Endogenous strains normally sterile sites
- Disease:
- Usually nosocomial
- UTIs, bacteremia, endocarditis, abdominal, and wound
- person-to-person, directly or via medical equipment --> nosocomial spread
- Multidrug resistance issues- AViridans Streptococci
- BEnterococcus sp.
- CStrep Anginosus
- DStreptococcus pneumonia
- EStreptococcus agalactiae
20Which one of the following fits this description?
- GPC
- Catalase negative
- Usually non-hemolytic, grey and translucent
- Non-fastidious
- PYR positive
- Group D
- Salt tolerance positive
- Bile esculin positive- AStrep Anginosus
- BStreptococcus pneumonia
- CStreptococcus pyogenes
- DStrep bovis
- EEnterococcus sp.
21Which one of the following fits this description?
- Bile esculin positive
- PYR negative
- NO GROWTH in 6.5% NaCl
- Non-fastidious- AStreptococcus pneumonia
- BStrep bovis
- CStrep Anginosus
- DEnterococcus sp.
22Which one of the following is;
- Often underestimated, unrecognized, and misidentified
- variability in bacteriological characteristics
- Normal upper respiratory flora
- Group A, C, F, G (or non)
- Abscesses in wound
- Rapid arginine +
- VP +
- Microaerophilic/anaerobic growth
- “minute” sized colonies
- caramel-like smell- AStrep bovis
- BStreptococcus agalactiae
- CStrep Anginosus
- DEnterococcus sp.
- EViridans Streptococci
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- Quiz on Lecture 7 Strep, created by persha.hossaini on 08/03/2015.
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- persha.hossaini
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- English
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