Quiz
Pharmacology X
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Questions in this quiz (34)
1Which of the following drugs is useful in treating dermatologic manifestations of an allergic response?
- Aa. Diazepam
- Bb. Atropine
- Cc. Hexylresorcinol
- Dd. Chlorpheniramine
- Ee. Phenoxybenzamine
2Cimetidine is used therapeutically to
- Aa. Stimulate respiration
- Bb. Protect against anaphylaxis
- Cc. Decrease gastric acid secretion
- Dd. Hasten excretion of barbiturates
- Ee. Dilate smooth muscles of the bronchioles
3Gastric acid secretion has been shown to be most effectively reduced with the use of
- Aa. Adrenal steroids
- Bb. Anticholinergic drugs
- Cc. Serotonin antagonists
- Dd. H1-histamine receptor antagonists
- Ee. H2-histamine receptor antagonists
4Drug-mediated inhibition of H2-histamine receptors is most useful in treating
- Aa. Asthma
- Bb. Anaphylaxis
- Cc. Contact dermatitis
- Dd. Gastric hyperacidity
- Ee. Localized allergic reactions
5Which of the following antihistamines is most commonly used as preoperative medication?
- Aa. Meclizine
- Bb. Cyclizine
- Cc. Promethazine
- Dd. Dimenhydrinate
- Ee. Chlorpheniramine
6Use of diphenhydramine (Benadryl) in controlling the symptoms of parkinsonism is based upon which of the following effects?
- Aa. Anticholinergic
- Bb. Local anesthetic
- Cc. Adrenergic-blocking
- Dd. CNS depressant on the midbrain
- Ee. Stimulant to dopaminergic nerves in the basal ganglia
7The mechanism of action of H1 antihistamines is
- Aa. MAO enzyme inhibition
- Bb. competitive antagonism
- Cc. physiologic antagonism
- Dd. noncompetitive antagonism
- Ee. inhibition of release of bound histamine
8Which of the following drugs is often used to treat trigeminal neuralgia?
- Aa. clonazepam
- Bb. carbamazepine
- Cc. acetazolamine
- Dd. succinylcholine
9The use of epinephrine for local hemostasis during surgery might result in
- Aa. hypoglycemia
- Bb. cardiac arrthymia
- Cc. an acute asthma attack
- Dd. a drastic drop in blood pressure
- Ee. any of the above
10The highest risk associated with use of oral contraceptives is
- Aa. hepatic necrosis
- Bb. permanent sterility
- Cc. cancer of the breast
- Dd. cancer of the uterus
- Ee. thromboembolic disorders
11Factors common to all forms of drug abuse include EXCEPT
- Aa. miosis
- Bb. tolerance
- Cc. physical dependence
- Dd. psychological dependence
- Ee. any of the above
12Alcoholic euphoria results from
- Aa. increased activity of the cerebellum
- Bb. increased activity of the cerebral areas
- Cc. increased activity of the spinal synapses
- Dd. decreased activity of the medullary centers
- Ee. removal of inhibitory activity of the cortex
13Sulfonyl ureas cause insulin secretion by
- Aa. adrenergic simulation
- Bb. cholinergic stimulation
- Cc. direct stimulation of pancreatic beta cells
- Dd. dependent of glucosa
14If a patient requiring an extraction reports that he is on dicoumarol therapy, the laboratory test most valuable in evaluating the surgical risk is
- Aa. clotting time
- Bb. bleeding time
- Cc. sedimentation rate
- Dd. complete blood cell count
- Ee. plasma prothrombin time
15A drug has a half-life of 4 hours. If 2 gms are given every 4 hrs what will be the amount in gms in the body immediately after the third dose?
- Aa. 1.5
- Bb. 2.0
- Cc. 3.5
- Dd. 4.0
- Ee. 6.0
16Which of the following combinations represents acceptable agonistantagonist pairs in antidotal therapy?
- Aa. morphine-naloxone
- Bb. dicoumarol-protamine
- Cc. warfarin-phenylbutazone
- Dd. carbon monoxide-carbon dioxide
17The various insulin preparations useful in the treatment of diabetes mellitus differ primarily in
- Aa. locus of action
- Bb. mechanism of action
- Cc. mode of transformation
- Dd. onset and duration of action
- Ee. none of the above
18Displacement of a drug from protein binding sites is expected to increase the
- Aa. drug effect observed
- Bb. duration of drug effect
- Cc. dose required for a given effect
- Dd. none of the above
19In an addisonian crisis (hypoaldosteronism) resulting from stress from a minor dental procedure, the patient should be treated immediately with
- Aa. 0.5 ml norepinephrine
- Bb. 5 mg. prednisolone acetate
- Cc. 1% triamcinolone acetonide
- Dd. 0.5 ml, 1:1000 epinephrine
- Ee. 2 ml (100 mg) hydrocortisone hemisuccinate
20Drug A inhibits the biotransformation of Drug B. The duration of action of drug B in the presence of drug A will usually be
- Aa. shortened
- Bb. prolonged
- Cc. unchanged
- Dd. equal
21In which of the following groups of drugs is there the most consistency in chemical structure?
- Aa. diuretics
- Bb. antiepileptics
- Cc. local anesthetics
- Dd. general anesthetics
- Ee. nonbarbiturate sedatives
22Cimetidine is administered to
- Aa. aid in sleeping
- Bb. relieve asthma
- Cc. inhibit gastric secretion
- Dd. relieve cold and flu symptoms
23Which of the following anticancer drugs can be classified as an antimetabolite?
- Aa. cisplatin
- Bb. lomustine
- Cc. vincristine
- Dd. methotrexate
24Which of the following hormones acts to elevate blood concentration of ionic calcium?
- Aa. glucagon
- Bb. parathyroid
- Cc. aldosterone
- Dd. thyrotropin
- Ee. thyrocalcitonin
25Disorientation, confusion, and hallucinations resulting from an overdose of scopolamine are most efficaciously treated by administering
- Aa. atropine
- Bb. levodopa
- Cc. acetylcholine
- Dd. physostigmine
26Developed hyporeactivity to a drug is
- Aa. tolerance
- Bb. antagonism
- Cc. detoxification
- Dd. desensitization
27Absorption of a drug from the intramuscular site of administration may be slowed by
a. excercise
b. vasoconstriction
c. the presence of congestive heart failure
d. administering the drug as an insoluble complex- A1. a and b
- B2. b only
- C3. b, c, and d
- D4. b and d
- E5. all of the above
28Salicylism includes which of the following?
a. nausea
b. tinnitus
c. vomiting
d. gastrointestinal bleeding- A1. a, b, and c
- B2. a, b, and d
- C3. a and c only
- D4. b, c, and d
- E5. all of the above
29Which of the following are important criteria for the adequate clinical evaluation of a new drug?
a. comparison with a placebo
b. evaluation of side effects
c. utilization of control groups
d. comparison with a standard drug
e. double blind experimental design- A1. a, b, c, and d
- B2. a, b, d, and e
- C3. a, c, d, and e
- D4. b, c, and e
- E5. b, d and e only
- F6. all of the above
30Each of the following agents has a long duration of action due to the presence of liver generated active metabolites EXCEPT
- Aa. diazepam
- Bb. oxazepam
- Cc. flurazepam
- Dd. chlordiazepoxide
31Each of the following statements relates to the general aspects of toxicology EXCEPT
- Aa. most drugs exert a single action
- Bb. toxicity is both time and dose dependent
- Cc. toxicity can be due to overdosage of a drug
- Dd. symptoms of toxicity can be anything ranging from nausea to death
- Ee. for some drugs, even a minimal concentration can be harmful
32The central actions of ethyl alcohol are not synergistic with which of the following?
- Aa. diazepam
- Bb. meperidine
- Cc. pentobarbital
- Dd. chlorpromazine
- Ee. methylphenidate
33A heroin dependent patient should not be given nalbuphine (Nubain) for pain because
- Aa. it has no analgesic properties
- Bb. it may produce respiratory depression
- Cc. as a mixed agonist-antagonist, it can elicit withdrawal symptoms
- Dd. the high abuse potential of nalbuphine may add to the patient's problems
34All of the following methods of drug biotransformation are classified as synthetic except:
- Aa. N-alkylation
- Bb. O-dealkylation
- Cc. sulfate conjugation
- Dd. glucuronide conjugation
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- Praxis Tests: Pharmacology Quiz on Pharmacology X, created by ACAPUN INSTITUTE on 08/11/2021.
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- ACAPUN INSTITUTE
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- Español
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- Created on 8 Nov 2021 · updated on 1 Aug 2022
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