Quiz
Anticoagulant and Antiplatelet Drugs
This quiz has question types that open in the usual player.
Questions in this quiz (26)
1Which of the following are the body's natural anticoagulants?
- AProtein C
- BProtein S
- CProtein A
- DProtein G
- EProtein M
- FAntithrombin
- GAntifibrin
- HAntiprothrombinase
- IAntithrombase
- JAntithrombomodulin
2[blank_start]Heparin[blank_end] is an anticoagulant drug which binds to one of the body's naturally occurring anticoagulants and up-regulates its action
- AHeparin
3Which naturally occurring anticoagulant of the body does Heparin bind to and potentiate?
[blank_start]Antithrombin[blank_end]- AAntithrombin
4Which two coagulation factors can be inhibited by unfractioned Heparin bound to antithrombin?
- AFactor Ia (Fibrin)
- BFactor IIa (Thrombin)
- CFactor IIIa
- DFactor IVa
- EFactor Va
- FFactor VIa
- GFactor VIIa
- HFactor VIIIa
- IFactor IXa
- JFactor Xa
5The difference between unfractioned Heparin and LMWH is that LMWH can only bind to one clotting factor, which is...
- AFactor Ia
- BFactor IIa
- CFactor IIIa
- DFactor IVa
- EFactor Va
- FFactor VIa
- GFactor VIIa
- HFactor VIIIa
- IFactor IXa
- JFactor Xa
6Which monitoring test should be used to measure the action of unfractioned Heparin?
- AProthrombin time
- BActivated Partial Thromboplastin Time (APTT)
- CAnti-Xa Assay
7Heparin can induce thrombocytopenia with thrombosis in long term use.
- ATrue
- BFalse
8Which of the following complications can be caused by long term Heparin use?
- AOsteoporosis
- BHypothyroidism
- CIron Deficiency Anaemia
- DB12 Deficiency Anaemia
- EAcute Myeloid Leukaemia
9Whilst Heparin reversal is usually conducted by simply stopping the heparin (short half life), in cases of major bleeding which drug can be given to reverse the antithrombin effect of heparin?
- AProtamine Sulphate
- BIV Ferrous Fibrinase
- CProthrombin Inducing Enzyme (PTIE)
- DCoagulating Factor III (CFIII)
10Warfarin is an anticoagulant which brings about the inhibition of [blank_start]Vitamin K[blank_end]
- AVitamin K
11Which clotting factors rely on Vitamin K for carboxylation?
- AFactor II
- BFactor III
- CFactor IV
- DFactor V
- EFactor VI
- FFactor VII
- GFactor VIII
- HFactor IX
- IFactor X
- JFactor I
12Warfarin administration should be conducted at the same time every day.
- ATrue
- BFalse
13Which testing method is used to measure the amount of Warfarin in an individual's system? (use acronym)
[blank_start]INR[blank_end]- AINR
14A normal INR is typically between
- A2.0-3.0
- B1.0-3.0
- C3.0-4.0
- D3.0-5.0
15Which two of the following should be given to a patient with suspect Warfarin toxicity?
- AVitamin K orally
- BVitamin K intravenously
- CFFP
- DProtamine Sulphate
- EPlatelet transfusion
16Rivaroxaban & Apixaban are direct inhibitors of which clotting factor?
- AFactor Ia
- BFactor IIa
- CFactor IIIa
- DFactor IVa
- EFactor Va
- FFactor VIa
- GFactor VIIa
- HFactor VIIIa
- IFactor IXa
- JFactor Xa
17Dabigatran is another type of new anticoagulant, providing direct inhibition of ...
- AProthrombinase
- BThrombin
- CProthrombin
- DFibrinogen
- EFibrin
- FFactor VIIIa
18In prophylaxis of elective hip/knee replacement surgery, which would be the most appropriate choice of medication?
- AWarfarin
- BLMWH
- CApixaban
19Structure of an artery from deep to superficial:
Tunica Intima = [blank_start]Endothelial Cells[blank_end]
Tunica Media = [blank_start]Smooth Muscle[blank_end]
Tunica Externa = [blank_start]Loose Fibrous Connective Tissue[blank_end]
Serosa = [blank_start]Epithelial Cells[blank_end]- AEndothelial Cells
- BSmooth Muscle
- CLoose Fibrous Connective Tissue
- DEpithelial Cells
20Atherosclerosis is damage to the endothelium resulting in plaque formation due to recruitment of 'foamy' [blank_start]macrophages[blank_end] which are rich in [blank_start]cholesterol[blank_end]
- Acholesterol
- Bmacrophages
21Which four of the following are risk factors for arterial thrombosis?
- ADiabetes
- BHypertension
- CSmoking
- DHigh HDL cholesterol
- EHigh LDL cholesterol
- FAtrial Fibrillation
- GAlcoholism
- HHyperthryoidism
22When there is endothelial damage, platelets bind to the subendothelial collagen via [blank_start]Glycoprotein 1b[blank_end] and [blank_start]Von Willebrand Factor[blank_end]
- AVon Willebrand Factor
- BPlatelet Adhesin
- CPlatelet Derived Growth Factor
- DProtein Disulfide Isomerase
- EGlycoprotein 1b
- FPlatelet Membrane Glycoprotein
- GITGA2B
- HHuman Platelet Antigen
23After binding to the subendothelial collagen, platelets begin to attach to each other via [blank_start]Glycoprotein IIb/IIIa[blank_end] and fibrinogen
- AGlycoprotein IIb/IIIa
- BGlycoprotein Ib
- CPlatelet Derived Growth Factor
24Antiplatelet drugs:
Clopidogrel = [blank_start]ADP receptor Antagonist[blank_end]
Aspirin = [blank_start]Cyclo-Oxygenase Inhibitor[blank_end]- ACyclo-Oxygenase Inhibitor
- BADP receptor Antagonist
25Antiplatelets such as Abciximab inhibit [blank_start]Glycoprotein IIb/IIIa[blank_end] thus inhibiting the [blank_start]aggregation[blank_end] stage of platelet plug formation
- Aaggregation
- Badhesion
- Cactivation
- DGlycoprotein IIb/IIIa
- EGlycoprotein Ib
- FADP
26Antiplatelet agents should be stopped [blank_start]7[blank_end] days prior to an elective operation.
- A7
Information
- Description
- Wednesdays 2 lectures in 1 quiz.
- Author
- Matthew Coulson
- Language
- English
- Views
- 851
- Tags
- Rating
- No ratings yet Rate this quiz