Test
General Pathoanatomy Final MCQs (301-400)- 3rd Year- PMU
Preguntas del test (100)
1Indicate the correct statement(s)
- Agranulation tissue is rich of capillaries and cells
- Bgranulation tissue is rich in collagen fibres and fibroblasts and contains less blood vessels
- Cgranulation tissue is the immature connective tissue
- Dfibrous tissue is immature connective tissue
2What is hyper-granulation?
- Amature connective tissue
- Bhypertrophic tumor-like cicatrix/scar
- Cgreater amount of granulation tissue
- Dnone of the above
3What is a scar?
- Ahypertrophic granulation tissue
- Bmature connective tissue
- Chypertrophic tumor-like cicatrix
- Dnone of the above
4What is a keloid?
- Ahypertrophic tumor-like cicatrix
- Bmature connective tissue
- Cgreater amount of granulation tissue
- Dnone of the above
5Which stain can be used to prove of scarring (cicatrix) of the heart?
- AVan Gieson
- BPeris
- CCongo Red
- DPAS
6Which of the could not be seen in rheumatoid nodules?
- AFibrinoid necrosis
- BEpitheloid cells
- CLanghans cells
- DLymphocytes
7Indicate the correct statement(s) for the polyarteriitis nodosa.
- Ait is an autoimmune disease
- Bit affects mostly the elastic arteries
- Cthere is accumulation of glucosaminoglycans in the vessel walls which can be demonstrated with metachromasia with Toluidin Bleu
- Dthe branches of the pulmonary arteries are affected
8Anaphylactic hypersensitivity reactions are related to:
- AHemolytic anemia
- BHashimoto thyroiditis
- CAllergic rhinitis
- DBronchial asthma
9Cytotoxic hypersensitivity reactions are related to:
- Ahashimoto thyroiditis
- Bhemolytic anemia
- Callergic rhinitis
- Dnodosal poyarteriitis
10Immune complexes mediated hypersensitivity reactions are related to:
- Apolyartheriitis nodosa
- Brheumatoid arthritis
- Chemolytic anemia
- Dtuberculosis
11Cell mediated hypersensitivity reactions are related to:
- ATuberculosis
- BPolyarteriitis nodosa
- CBronchial asthma
- DHashimoto thyroiditis
12Indicate characteristics of the benign tumors.
- Aexpansive type of growth
- Bfast speed of growth
- Cinvading and destroying the adjacent tissues
- Din general they have good prognosis
13 Indicate characteristics of the benign tumors
- Ainfiltrative growth
- Bslow, long term developntcnt
- Cusually they don't recur after complete surgery
- Dtheir microscopic structure shows only tissue atypia
14Indicate correct characteristics of the malignant tumors.
- Aexpansive growth
- Bfast speed of growth
- Cthey have poor prognosis in general
- Dcomposed of differentiated, mature cells
15Indicate correct characteristics of the malignant tumors.
- Ainfiltrative growth
- Bmicroscopic structure shows both tissue and cells atypia
- Cgood prognosis in general
- Dmetastasizing
16Which is the most common way of metastasizing of epithelial tumors?
- Aby lymphatics (lymphogenic metastases)
- Bwith blood (hematogenic metastases)
- Cby cerebrospinal fluid
- Dnone of the above
17What is papilloma?
- Amalignant tumor of the covering epithelium
- Bbenign tumor of glandular epithelium
- Cbenign tumor of cover type epithelium
- Dbenign soft tissue tumor
18Indicate the correct characteristic(s) for papilloma
- Ait has tree-like stroma covered by differentiated stratified squamous epithelium
- Bit has tree-like stroma covered by undifferentiated squamous epithelium with signs of cell atypia
- Cstroma and parenchyma are difficult to distinguish
- Dit doesn't have a capsule
19What is the term used for malignant tumors of cover type epithelium?
- Aadenocarcinoma
- Bpapilloma
- Ccarcinoma
- Dsarcoma
20What is the term used for malignant tumors of glandular type epithelial origin?
- Aadenocarcinoma
- Badenoma
- Ccarcinoma
- Dcarcino-adenoma
21What is the term used for benign tumors of glandular type epithelial origin?
- Apapilloma
- Badenoma
- Cteratoma
- Dadenocarcinoma
22Point the correct statement(s) about basal cell carcinoma.
- Ait develops only on the skin
- Bit can develop at any place with squamous epithelium
- Cit characterizes with early lymphogenic and hematogenic metastases
- Dvery often it recurs at the same place after surgery
23Keratinized squamous cell carcinoma:
- Adevelops only on the skin
- Bcan develop at any place with squamous epithelium
- Cis highly undifferenciated malignant tumor
- Dis a tumor composed of more differenciated cells with keratin production
24What kind of structures are the cancer perls?
- Aaccumulation of keratin produced by more differentiated malignant cells originating from squamous epithelium
- Bpink-coloured homogenous substance located in the centre of the tumor nests
- Caccumulation of mucus produced by highly undifferentiated malignant cells located in the centre of the tumor nests
- Dpink homogenous substance that accumulates in the stroma of the tumor
25The gross appearance of which tumor is called "ulcus rodens"?
- Asquamous cell carcinoma
- Bmelanoma
- Cbasal cell carcinoma
- Dadenocarcinoma
26Squamous cell carcinoma develops in the lung after:
- Aacute bronchitis
- Bchronic bronchitis accompanied by metaplasia
- Cbronchial asthma
- Dinhalaton of a foreign body
27Indicate the correct microscopic features of cell atypia
- Apolymorphism of cells and nuclei
- Blow nucleus-cytoplasm index
- Ctypical mitoses
- Dmonster cells, hyperchromasia and polychromasia of nuclei
28What are the characteristics of the nuclei of the malignant tumors?
- Apolychromasia
- Bnormal staining pattern
- Chyperchromasia
- Dincreased nucleo-cytoplasmic index
29Papillary carcinoma of the urinary bladder arises from:
- Asquamous epithelium
- Btransitional epithelium
- Cglandular epithelium
- Dsmooth musculature
30What is carcinoma in situ?
- Amalignant tumor limited to the epithelium above the basal membrane
- Bmalignant tumor destroying the basal membrane but spreading no more than 5mm below it
- Cbenign tumor limited to the basal membrane
- Dbenign tumor of a great size compressing the surrounding tissues
31What type of atypia could be seen in the benign tumors of glandular epithelium?
- Atissue atypia
- Bcell atypia
- Cboth tissue and cell atypia
- Dnone of the above
32Which staining is used for proving mucus production from gelatinous adenocarcinoma?
- ACongo red
- BToluidin bleu, metachromasia is demonstrated
- CPAS reaction with amylase control
- DVan Gieson
33Pericanalicular and intracanalicular are types of:
- ADuctal carcinoma of the breast
- BPaget's disease
- CRenal cell carcinoma
- DFibroadenoma
34Kruckenberg tumors are:
- Ametastases from colon adenocarcinoma in the ovaries
- Bmetastases from pancreatic adenocarcinoma in the ovaries
- Cmetastases from gastric carcinoma in the ovaries
- Dmetastases from hepatocellular carcinoma in the ovaries
35Pleomorphic adenoma could be seen mainly:
- Ain the parotid gland
- Bin the minor salivary glands
- Cin the stomach
- Din the thyroid gland
36Indicate the correct statements about fibroadenoma of the breast.
- Acapsulated and lobulated tumor
- Bnon-capsulated malignant tumor with invasive growth
- Cmicroscopically it has two types -- intracanalicular and pericanalicuJar
- Dseen in older women
37Mark the correct statements about papillary cystadenoma of the ovary:
- Amalignant tumor
- Bhas cyst-like and papillary structures
- Chistological characteristics include serous and mucinous types
- Dit is a physiological change related to menstrual cycle
38'Linitis plastica' is a gross subtype of:
- Agastric cancer
- Bpancreatic cancer
- Cbreast cancer
- Duterine cancer
39Grossly adenocarcinoma of the colon can be:
- Apolypoid
- Bulcerous
- Cnodular
- Dall of the listed above
40The terms "early cancer" and "advanced cancer" are used for:
- Agastric adenocarcinoma
- Badenocarcinoma of the endometrium
- Cadenocarcinoma of the colon
- Dbreast cancer
41Malignant tumors from soft tissue are called:
- Acarcinomas
- Bword for tissue origin+ suffix " —oma"
- Csarcomas
- Dteratomas
42Indicate the characteristics of the sarcomas.
- Aseen in older age
- Bgrossly they look like "fish meat"
- Cthey give early hematogenic metastases
- Dparenchyma and stroma are equally distributed
43Mark the characteristics of the carcinomas.
- Aseen in young people
- Bthey metastasize by the blood flow first
- Cgrossly they have granular surface
- Dparenchyma and stroma are equally distributed
44What kind of sarcoma could be seen in an immune deficiency?
- AKaposi sarcoma
- BEwing sarcoma
- CRhabdomyosarcoma
- DChondrosarcoma
45Which of the following sarcomas have the worst prognosis?
- Aliposarcoma
- Bostesarcoma
- Cfibrosarcoma
- Dleiomysarcoma
46What staining can be used to distinguish leiomyoma uteri from fibroma?
- ACongo red
- BPerls
- CPAS reaction with PAS control
- DVan Gieson
47Point the characteristics of the leiomyosarcoma.
- Apolymorphism of cells and nuclei
- Bhyper- and polychromasia of nuclei
- Ctypical mytoses
- Dmonster cells
48What is hybernoma?
- Abenign tumor of vascular origin
- Bbenign tumor originating from brown fat tissue
- Cbenign tumor originating from striated muscles
- Dmalignant tumor originating from pigment tissue
49What are the signs of the atypia in a nevus?
- Aasymmetry of the lesion, irregular borders
- Bdark color, irregular color of the lesion
- Cdiameter less than 5mm
- Dregular borders
50How should a biopsy be done if there is a suspicion for the melanoma?
- Aincision biopsy
- Bpunch biopsy
- Cexcision biopsy
- Dbrush biopsy
51Point the most common localizations of the teratomas.
- Aovaries, testis
- Bextremities
- Cretroperitoneum
- Dmediastinum
52Which of the following are organoid teratomas
- Anephroblastoma
- Bcholesteatoma
- Cdermoid cyst
- Dbranchiogcnic cyst
53Which of the following is organismoid teratoma
- Aepidermoid cyst
- Bteratocarcinoma
- Cdermoid cyst
- Dnefroblastoma
54What is a nevus pigmentosus?
- Atumor-like process
- Btumor process
- Cmicroscopically it contains mature melanocytes
- Dmicroscopically it contains cells with signs of severe atypia and some of them contain melanin
55What is a melanoma?
- Amalignant congenital tumor
- Bbenign tumor composed of melanocytes
- Cmalignant tumor of pigment origin
- Dnone of the above
56What is an achromatic melanoma?
- Abenign form of melanoma
- Bmelanoma without melanin in the tumor cells
- Ctype of melanoma which can be proved with immunohistochemical tests
- Dmelanoma which is more differentiated
57Point possible localizations of the nevus pigmentosus and melanoma.
- Askin
- Buvea
- Cmeninges
- Dall of the above
58Lentigo maligna, nodular, superficial, acral lentigenous are gross forms of:
- Amelanoma
- Bsquamous cell carcinoma of the skin
- Cbasal cell carcinoma of the skin
- Dnevus pigmentosus
59Indicate immunohistochemical stains to prove melanoma
- AHMB-45
- BCa-125
- CS-100
- DCytokeratin
60Which of the following tumors do not have a stroma
- Achoriocarcinoma
- Bseminoma
- Cnephroblstoma
- Dneuroblastoma
61Indicate types of nevus pigmentosus:
- Aacquired and congenital
- Bjunctional, compound, intradermal
- Cbenign and malignant nevus
- Dectodermal and endodermal nevus
62Melanin is:
- Alipidogenic pigment
- Bproteinogenic pigment
63Where is lipofuscin deposited?
- Aintracellularly
- Bextracellularly
64The frozen section ('gefrir') is:
- Arapid 'intraoperative' histological diagnosis
- Brapid cytology method
- Ctype of medical imaging
- Dhistochemical method
65The term „pathognomonic change" means:
- Aunexplained change
- Bparadoxical change
- Csufficient to identify the diagnosis/lesion
- Ddiffuse inflammatory change
66Most likely the cause of centrolobular fatty degeneration of hepatocytes is:
- Adiabetes
- Bintoxication
- Chypoxia
- Doverfeeding
67Hyaline — droplet degeneration has following characteristics:
- Aextracellular
- Bintracellular
- Cprotein accumulation
- Dcarbohydrate accumulation
68What pigment is formed in the center of the hematoma?
- Ahemosiderin
- Blipofuscin
- Chemomelanin
- Dhematoidin
69In which blood vessels are formed most frequently mixed thrombi?
- Alarge veins
- Barteries
- Ccapillaries
- Dvenules
70Squamous cell carcinoma occurs most frequently in:
- Astomach
- Bskin
- Cbladder
- Dlarynx
71Hyperemic-hemorrhagic zone occurs in:
- Atophi urici
- Bnodular amyloidosis
- Canemic infarction
- Dpneumonia
72Which types of bleeding occur in the digestive system?
- Ahemothorax
- Bhemoptysis
- Cmelena
- Dhematemesis
73Which of the following cell damages are irreversible?
- Anecrosis
- Bapoptosis
- Cvacuolar degeneration
- Dcellular edema
74Left ventricular hypertrophy can develop in:
- Acor pulmonale
- Bsystemic hypertension
- Cmitral stenosis
- Daortic stenosis
75Cancer cells which show no resemblance to the tissue from which the tun originates are called:
- Aundifferentiated carcinoma
- Bwell-differentiated carcinoma
- Cscirrhous type carcinoma
- Dhistioid cancer
76Which of the following is correct for the mechanical jaundice?
- Aindirect bilirubin prevails in blood
- Belevated urine urobilinogen
- Celevated urine bilirubin
- Dstools are hyperpigmented
77Basal cell carcinoma is localized most frequently on:
- Athe skin of the forearm
- Bthe skin of the lower limbs
- Cthe skin on the palms
- Dskin of the face
78Caseous necrosis is characteristic for:
- Aspecific inflammation
- Btuberculosis
- Cenzyme fat necrosis
- Dchronic pyelonephritis
79Bilaterally, on the skin of the eyelids of a young woman are seen yellow nodules with the size of a grain of rice. What is it?
- Axanthelasmas
- Bnevus
- Cefelides
- Dhemosiderin deposition
80Which of the following are protein accumulations?
- Ain the epithelial cells of renal tubules
- Brussel bodies
- Cbodies of Mallory
- Dasteroid cells
81Hemorrhagic infarction develops in:
- Aorgans with end type arteries (end type blood supply)
- Bblockage of arterioles
- Cprevious venous stasis
- Dorgans with double blood supply
82How do we call the local depigmentation of the skin?
- Avitiligo
- Bhemosiderosis
- Calbinism
- Dohronosis
83What kinds of techniques are used for the detection of the lipids:
- Afreezing microtome
- Bparaffin method
- Calcohol fixation
- Dstaining with Sudan Ill
84The sequence of local structural changes in a disease is called
- Asanogenesis
- Bpathogenesis
- Ctanatogenesis
- Dmorphogenesis
85" Tiger Heart " is diagnosed when:
- Asubepicardial fat is increased
- Byellowish lines in the papillary muscles are seen
- Cthe interventricular septum is injured
- Dinfarcted area of the left ventricle in seen
86Which of the following is correct for the mechanical jaundice:
- Ait is parenchymal jaundice
- Bthere is posthepatic occlusion
- Cdirect bilirubin is increased
- Dit is also called hemolytic jaundice
87The risks involved in fast draining of large quantities of acistes are:
- Adevelopment of low oncotic pressure edema
- Bbleeding into the abdominal cavity
- Cmassive arterial hyperemia in the abdominal vessels
- Dhemodynamic collapse
88"Mutilation" means :
- Aform of biological mutation
- Bpendulum movement of the blood
- Czonal hair loss
- Dself amputation of phalanges
89It is true that :
- Aconcentric hypertrophy is also called tonogenic
- Beccentric hypertrophy is myogenic
- Chypertrophy can be combined with hyperplasia
- Dfalse type of hypertrophy is hyperplasia
90Sources of fat embolism in the lung are
- Athe bone marrow in the long bones
- Bsubcutaneous fat
- Cliver with fatty degeneration
- Dulcerated atherosclerotic plaque of the aorta
91Which of these factors lead to nutmeg liver?
- Ashort venous stasis
- Barterial hyperemia
- Cchronic venous congestion
- Dmitral stenosis
92In the bronchi and nasal cavity may develop squamous cell carcinoma based on:
- Ahypoplasia
- Bhistological accommodation
- Canaplasia
- Dmetaplasia
93Amyloid demonstates following characteristics:
- Aidentified with Tioflavin S in fluorescence
- Bshows metachromasia with Perls
- Cidentified with Congo rot in polarized light
- Dultrastructurally has fibrillary structure
94Anaphylactic shock occurs in:
- Ahypersensitivity reactions cytotoxic type
- Bresponse induced by immune complexes
- Catopic reactions
- Ddelayed type hypersensitivity
95A basal cell carcinoma is localized most frequently on:
- Athe skin of the forearm
- Bthe skin of the lower limbs
- Cthe skin on the palms
- Dthe skin of the face
96Reaction for Prussian blue is used for:
- Atattoos
- Bproof of bilirubin
- Cproof of hemosiderin
- Din hemochromatosis
97How could an air embolism be proved:
- Ain the presence of witnesses
- Bautopsy in a bathtub
- Cpuncturing the right ventricle
- Dpuncturing of the left ventricle
98Which enzymes are involved in a melanogenesis?
- Ahyaluronidase
- Btvrosinase
- Cdopa oxidase
- Dlipase
99Infarctions of which organs could often lead to the death of the patient?
- Arenal infarction
- Binfarction of the spleen
- Cinfarction of heart
- Dcerebral infarction
100In cancers with epithelial origin:
- Acells are arranged in sheets, nests or cords
- Bresemble 'fish meat'
- Cmetastasize primarily by blood
- Dcells show atypia
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- General Pathoanatomy Final MCQs (301-400)- 3rd Year- PMU
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- Med Student
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