Biochem Sem 2 - alcohol

Descripción

biochem Test sobre Biochem Sem 2 - alcohol, creado por Alannah McDonnell el 26/02/2018.
Alannah McDonnell
Test por Alannah McDonnell, actualizado hace más de 1 año
Alannah McDonnell
Creado por Alannah McDonnell hace alrededor de 6 años
342
2

Resumen del Recurso

Pregunta 1

Pregunta
How much alcohol is absorbed in the stomach
Respuesta
  • 20%
  • 90%
  • 5%
  • 0.5%

Pregunta 2

Pregunta
How much alcohol is metabolized by the liver?
Respuesta
  • 20%
  • 90%
  • 5%
  • 0.5%

Pregunta 3

Pregunta
How much alcohol is excreted by urine?
Respuesta
  • 20%
  • 90%
  • 5%
  • 0.5%

Pregunta 4

Pregunta
How is alcohol absorbed along the entire GI tract?
Respuesta
  • simple diffusion
  • active transport
  • osmosis
  • ion gated channels

Pregunta 5

Pregunta
What do alcoholic beverages primarily consist of?
Respuesta
  • water
  • starch
  • ethanol
  • sugar
  • protein
  • lipids

Pregunta 6

Pregunta
Which of these factors will allow you to drink more alcohol for a lower blood alcohol level content?
Respuesta
  • weight
  • Male
  • Female
  • empty stomach
  • full stomach
  • carbonated mixers

Pregunta 7

Pregunta
Which of the following statements is true?
Respuesta
  • Class 1 ADHs have a low Km for ethanol
  • Class 1 ADHs have the lowest specificity for EtOH
  • CYP2E1 has a lower Km for ethanol than class 1 ADHs
  • Chronic alcohol consumption suppresses P450 enzyme systems
  • Acute effects of ethanol arise from the increased NAD+/NADH ratio

Pregunta 8

Pregunta
What are the two primary pathways of alcohol metabolism? C[blank_start]ytosol[blank_end] A[blank_start]lcohol[blank_end] D[blank_start]ehydrogenade[blank_end] (ADH) M[blank_start]icrosomal[blank_end] ethanol-o[blank_start]xidizing[blank_end] s[blank_start]ystem[blank_end] (MEOS)
Respuesta
  • Cytosol
  • cellular
  • Alcohol
  • Adenine
  • Dehydrogenase
  • Deoxygenated
  • Dehydrator
  • Microsomal
  • Marcoscopic
  • oxidizing
  • oxidation reaction
  • system
  • series

Pregunta 9

Pregunta
Which pathway is used for beaking down small amounts of alcohol?
Respuesta
  • Cytosol Alcohol Dehydrogenase
  • Microsomal Ethanol-oxidizing system

Pregunta 10

Pregunta
Which pathway is important for breaking down large amounts of alcohol?
Respuesta
  • Microsonmal Ethanol-Oxidizing System
  • Alcohol dehyrogenase

Pregunta 11

Pregunta
What can alcohol be metabolized to in the colon?
Respuesta
  • ethanol
  • acetaldehyde
  • starch
  • dangerous bacteria

Pregunta 12

Pregunta
What is the alcohol metabolized by in the colon?
Respuesta
  • Colon Bacterial ADH
  • Bacteria
  • amalase
  • MEOS

Pregunta 13

Pregunta
What is acetaldehyde?
Respuesta
  • a toxic compound
  • a non-toxic compount

Pregunta 14

Pregunta
What is one major effect of low doses of alcohol?
Respuesta
  • slowing the citric cycle
  • use of MEOS
  • chance of alcoholism
  • stomach issues

Pregunta 15

Pregunta
*** what is alcohol dehydrogenase?
Respuesta
  • a family of isoenzymes
  • cool

Pregunta 16

Pregunta
Which ADH has the highest specificity for ethanol?
Respuesta
  • class 1 ADHs
  • class 2 ADHs
  • class 4 ADHs
  • they're all equal

Pregunta 17

Pregunta
How many genes are there for class 1 ADH?
Respuesta
  • 1
  • 2
  • 3
  • 4
  • 5

Pregunta 18

Pregunta
What do the genes for class 1 ADH exist as?
Respuesta
  • allelic variants
  • polymorphisms

Pregunta 19

Pregunta
which ADH class is high in the liver?
Respuesta
  • 1
  • 2
  • 3
  • 4

Pregunta 20

Pregunta
what ADH class can be found in GIT?
Respuesta
  • 1
  • 2
  • 3
  • 4

Pregunta 21

Pregunta
which of these two are functional polymorphisms
Respuesta
  • ADH 1A and ADH 1C
  • ADH 2A and ADH 1C
  • ADH 1X and ADH X

Pregunta 22

Pregunta
***what can partially account for observed differences in ethanol elimination rates among individuals or population?
Respuesta
  • functional polymorphisms
  • eating habits

Pregunta 23

Pregunta
Possession of which allele is associated with decreased susceptibility to alcoholism?
Respuesta
  • ADH 1B*2
  • ADH 1B*3
  • ADH 1A*2
  • ADH 1A*3

Pregunta 24

Pregunta
What does ADH1B*2 code for?
Respuesta
  • a relatively fast ADH
  • a relative slow ADH

Pregunta 25

Pregunta
ALDH = A[blank_start]cetaldehyde[blank_end] D[blank_start]ehydrogenase[blank_end]
Respuesta
  • cetaldehyde
  • ehydrogenase

Pregunta 26

Pregunta
What type of ALDH is cytosolic?
Respuesta
  • ALDH 1
  • ALDH 2
  • ALDH 3

Pregunta 27

Pregunta
What does accumulation of acetylaldehyde cause?
Respuesta
  • nausea
  • vomiting
  • chest pains
  • hunger
  • thirst

Pregunta 28

Pregunta
What can an ALDH inhibitor be used for?
Respuesta
  • Drug treatment for alcoholism
  • cure for thirst
  • it can't be used for anything, it's toxic
  • liver repair

Pregunta 29

Pregunta
what does metabolism of acetate require?
Respuesta
  • activation to acetyl CoA
  • deactivation from acetyl CoA
  • reduction of Fatty Acids
  • removal of a phosphate group
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