447561
Descripción
Test por gina_evans0312, actualizado hace más de 1 año
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Creado por gina_evans0312
hace más de 10 años
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Pregunta 1
Pregunta
What is the main role of cytochrome aa3?
Respuesta
-
Takes e- from ubiquinol and reduces oxygen to water
-
Takes e- from ubiquinol and reduces oxygen to peroxide
-
Takes e- from cytochrome c and reduces oxygen to peroxide
-
Takes e- from cytochrome c and reduces oxygen to water
Pregunta 2
Pregunta
Complex IV contains how many subunits?
Respuesta
-
12
-
13
-
14
-
15
Pregunta 3
Pregunta
Complex IV doesn't transfer protons across the inner mitochondrial membrane
Respuesta
- True
- False
Pregunta 4
Pregunta
Which ions does it contain, and how many of each?
Respuesta
-
2 Fe (in haeme groups) and 3 Cu (2 as a Cu-Cu binuclear centre, 1 as a binuclear Fe-Cu centre)
-
2 Cu (in haeme groups) and 3 Fe (2 as a Fe-Fe binuclear centre, 1 as a binuclear Fe-Cu centre)
-
2 Mg (in haeme groups) and 3 Cu (2 as a Cu-Cu binuclear centre, 1 as a binuclear Fe-Mg centre)
Pregunta 5
Pregunta
Cytochrome aa3 complex consists almost entirely of alpha helices
Respuesta
- True
- False
Pregunta 6
Pregunta
Put the following in order
A- Cyt c
B- CuA centre
C- Cyt a
D- Cyt a3-CuB centre
E - Water
•Transfer from cyt a3-CuB centre to oxygen
Respuesta
-
A-B-C-D-E
-
A-C-D-B-E
-
A-C-B-D-E
Pregunta 7
Pregunta
How many protons are pumped by complex 4, and how many are used to make water (per Oxygen molecule)?
Respuesta
-
4 & 4
-
4 & 2
-
2 & 4
Pregunta 8
Pregunta
Which conformation of Complex IV has the low affinity for protons?
Respuesta
-
Conf. A
-
Conf. B
-
Conf. C
Pregunta 9
Pregunta
Protons bind to Complex IV during Conformation B
Respuesta
- True
- False
Pregunta 10
Pregunta
What happens during conformation B that lowers the Complex IV's affinity for protons?
Respuesta
-
Energy is put in
-
Energy is lost
-
The protein has an Fe group added
Pregunta 11
Respuesta
-
Okay?
-
Done
Pregunta 12
Pregunta
ATP synthase is found on the inner mitochondrial membrane
Respuesta
- True
- False
Pregunta 13
Pregunta
ATP synthase is divided into two sections, F1 & F0
Which is peripheral and which is integral?
Respuesta
-
F1 is peripheral F0 is integral
-
F0 is peripheral F1 is integral
Pregunta 14
Pregunta
Name the function of ATP synthase
Respuesta
-
ATP synthesis
-
ATP hydrolysis
-
ATP translocation
-
Proton translocation
Pregunta 15
Pregunta
If ATP is high, and the proton gradient is low, what will Complex V do instead?
Respuesta
-
Hydrolyse ATP
-
Synthesise GTP
-
Break itself down
Pregunta 16
Pregunta
Protons flow through F1 to power the ATP synthesis in F0
Respuesta
- True
- False
Pregunta 17
Pregunta
Name the subunits of F1
Respuesta
-
Alpha-Epsilon
-
A-E
-
1-5
Pregunta 18
Pregunta
Which of the following subunit(s) are the largest in F1?
Respuesta
-
Alpha & Beta
-
Gamma & Delta
-
Beta and Gamma
-
Alpha and Epsilon
Pregunta 19
Pregunta
What is the role of the delta subunit in F1?
Respuesta
-
Stabiliser for the F1 head
-
ATP synthesis
-
Connets F1 too F0
Pregunta 20
Pregunta
The epsilon subunit of F0 connects the gamma to the C subunit
Respuesta
- True
- False
Pregunta 21
Pregunta
F0 contains how many subunits?
Respuesta
-
2- A & B
-
3- A, B & C
-
2- Alpha & Beta
Pregunta 22
Pregunta
The F1 subunit is...
Respuesta
-
8nm long
-
18nm long
-
12nm long
-
90nm wide
-
19nm wide
-
9nm wide
Pregunta 23
Pregunta
The Y subunit of F1 is made of 2 beta sheets that have been bent, but are bound at the base
Respuesta
- True
- False
Pregunta 24
Pregunta
When the gamma subunit is in contact with a beta subunit, the ATP catalysis site is in it's _ formation
Respuesta
-
Open
-
Loose
-
Tight
Pregunta 25
Pregunta
A subunit contains ADP + Pi- what conformation is it in?
Respuesta
-
Loose
-
Tight
-
Open
Pregunta 26
Pregunta
Whilst the subunit is replacing ATP with ADP + Pi, the gamma subunit remains in plance
Respuesta
- True
- False
Pregunta 27
Pregunta
What order do the three conformations work in?
Assume you start with the Loose formation
Respuesta
-
Loose-Tight-Open
-
Loose-Open-Tight
Pregunta 28
Pregunta
State the characteristics of the C subunit of F0
Respuesta
-
Small
-
Large
-
Hydrophobic
-
Hydrophilic
-
Integral
-
Peripheral
Pregunta 29
Pregunta
How many monomers make up the C subunit?
Respuesta
-
8-12
-
8-10
-
4-10
Pregunta 30
Pregunta
The C subunit contains 3 rings of monomer
Respuesta
- True
- False
Pregunta 31
Pregunta
Why is there a variance across species of the number of monomers in the C subunit?
Respuesta
-
The more complex an organism, the more efficient the subunit
-
The more complex an organism, the less efficient the subunit
-
The larger the organism, the more subunits are required
-
Mammals have 8, birds have 12, all lesser animals and prokaryotes have 14 or more
Pregunta 32
Pregunta
More subunits require more protons to move them, so more subunits is less efficient
Respuesta
- True
- False
Pregunta 33
Pregunta
How is the A subunit described?
Respuesta
-
A proton half channel
-
A proton channel
-
A proton quarter channel
Pregunta 34
Pregunta
Protons passing through the A subunit...
Respuesta
-
Use it to enter the C subunit and exit to the cytoplasm
-
Use it to exit into C subunit and enter from the cytoplasm
Pregunta 35
Pregunta
Each subunit can hold 2 protons
Respuesta
- True
- False
Pregunta 36
Pregunta
The momevent of the protons around the C subunit powers what?
Respuesta
-
The movement of the gamma subunit
-
The conformational changes of the beta subunits
-
The attachment of the alpha subunits
-
The rotation of the delta subunit
Pregunta 37
Pregunta
The rotation of the F1 has been proved by attaching a microtubule filament to the F1 head and examining it under the microscope
Respuesta
- True
- False
Pregunta 38
Pregunta
Only the gamma subunit of the F1 complex rotates
Respuesta
- True
- False
Pregunta 39
Pregunta
How is the Alpha/Beta spheroid of F1 held in place?
Respuesta
-
B1 subunit
-
B2 subunit
-
Epsilon subunit
-
Delta subunit
Pregunta 40
Pregunta
For every _degree rotation, 1 molecule of ATP is produced
Respuesta
-
90
-
120
-
180
-
360
Pregunta 41
Pregunta
The mechanism of the gamma subunit causes an affinity change for ATP/ADP + Pi, driving the cycle
Respuesta
- True
- False
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