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A & P Lecture Test #3
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- 1Name the Organs that make up the Muscular System (4ish)Skeletal Muscles
Hollow Organs w/ Smooth Muscle
Heart
Blood Vessels, Nerves, and CT's - 2Basic functions of the Muscular System (6)Movement
Maintain body posture
Maintain body temp
Stabilize Synovial Joints
Support soft tissue
Guard entrances and exits of the body - 3Name the 3 types of muscle tissueSkeletal
Cardial
Smooth - 4Define the 4 characteristics all muscle tissues share1. Contractility- Can contract/shorten
2. Excitability- Respond to stimuli
3. Extensibility- Muscle brought back to original length by opposing muscle contracting
4. Elasticity- Can recoil after shortening - 5Name the 2 synonyms for Muscle CellsMuscle Fiber
Myocyte - 6Define Autorhythmic CellsCells that can contract on their own without a stimulus from a neuron or hormone
- 7Gap junctions + Desmosomes=Intercalated disks
- 8Name the type of Muscle(s) that: Have parallel protein fibers, striations, and t-tubulesSkeletal and Cardiac
- 9Name the type of Muscle(s) that: Have cells that DON'T branch and have no intercalated disksSkeletal and Smooth
- 10Name the type of Muscle(s) that: Have involuntary control and have autorhythmic cellsCardiac and Smooth
- 11Name the type of Muscle(s) that: Have Actin, Myosin, Tropomyosin and TroponinSkeletal and Cardiac
- 12Name the type of Muscle(s) that: Has voluntary control and has 300 Mitochondria per cellSkeletal muscle
- 13Name the type of Muscle(s) that: Has no autorhythmic cells and has 100's of Nuclei per cellSkeletal
- 14Name the type of Muscle(s) that: Has most of it's Ca+2 stored in its Sarcoplasmic Reticulum and has Nuclei on the edges of its cellsSkeletal
- 15Name the type of Muscle(s) that: Has more than 300 Mitochondria per cell and 1-2 Nuclei per cellCardiac
- 16Name the type of Muscle(s) that: Stores most of its Ca+2 in its interstitial fluid and has Nuclei in the center of its cellsCardiac and Smooth
- 17Name the type of Muscle(s) that: Does NOT have Troponin or striationsSmooth
- 18Name the type of Muscle(s) that: Has less than 300 Mitochondria per cell and 1 Nucleus per cellSmooth
- 19Name the type of Muscle(s) that: Has no T-tubules and short, spindle shaped cellsSmooth
- 20Name the type of Muscle(s) that: Randomly arranged protein fibersSmooth
- 21Name the type of Muscle(s) that: Has long fibrous cellsSkeletal
- 22Name the type of Muscle(s) that: Has medium, branched cellsCardiac
- 23Where are Skeletal muscles located?Attached to bones, some are attached to subcutaneous layer
- 24Where are Cardiac muscles located?Wall of the heart
- 25Where are Smooth muscles located?BV's, walls of hollow organs (not heart), arrector pili, iris of the eye, ciliary muscle of the eye
- 26Function of Skeletal muscles?Voluntary movement
Facial expressions - 27Function of Cardiac muscles?Create pressure needed to pump blood
- 28Function of Smooth muscles?Move blood, food, waste
Regulate diameter of an organ - 29What protein fibers make up: Thick Myofilaments? Thin Myofilaments?-Myosin
-Mostly Actin; Some Troponin and Tropomyosin - 30Function of Thick Myofilaments? Think Myofilaments?During muscle contractions:
-Pull Thin Myofilaments to the center of the Sarcomere
-Are pulled towards the center of the Sarcomere to shorten the muscle - 31Function of Myofibrils?Shorten during muscle contractions in order to make the entire muscle shorten
- 32Structure of Thick Myofilaments?100's of Myosin proteins; 2 heads and 1 long tail
- 33Structure of Thin Myofilaments?2 strands of Actin twisted into a Helix w/ 2 Tropomyosin strands and scattered Troponin complexes
- 34Structure of Sarcomeres?Repeating units of Thick and Thin Myofilaments
- 35Myofibrils are made of repeating units of _____________ arranged side to sideSarcomeres
- 36Muscle fibers are made of repeating units of ___________ arranged ___________Myofibrils, Parallel
- 37Muscle fascicles are groups of ____________ _____________ bundled togetherMuscle fibers
- 38This structure is made of Dense Irregular CT that surrounds the entire skeletal muscleEpimysium
- 39This structure is made of Dense Irregular CT that surrounds each muscle fasciclePerimysium
- 40What is the Endomysium and what is it made out of?Areolar CT that surrounds each muscle fiber/cell
- 41This structure is a big sheet of Dense Irregular CT that surrounds the Epimysium, Perimysium, and EndomysiumDeep Fascia
- 42Tendons are made of what kind of tissue? What do tendons do?Dense Regular CT
Connect muscle to bone, cartilage, skin, etc - 43Aponeuroses are made of what kind of tissue? What do they do?Dense Regular CT
Same as tendons; but they are found in sheetlike muscles - 44The cell membrane of a muscle fiber is called what? Function?Sarcolemma
Contain ligand-gated ion channels - 45The Cytoplasm of a Muscle cell is called what?Sarcoplasm
- 46Define Sarcoplasmic Reticulum and tell its functionThe Smooth ER of a muscle cell
Storage and release of Ca+2 ions - 47This structure is a narrow tube filled w/ ECF that reaches into the Sarcoplasmic ReticulumT-Tubules/Transverse Tubules
- 48Function of T-Tubules?Spread electrical impulses thru the muscle fiber quickly
- 49This structure is the end of the Sarcoplasmic Reticulum and is what releases the Ca+2 ions during a muscle contractionCisternae
- 50T-Tubules + Cisternae =Triad
- 51The smallest contractile unit of a skeletal or cardiac muscle fiber is what?Sarcomere
- 52Name the 3 parts of a Sarcomere that change when a muscle contracts and how they change1. H-zone disappears
2. I-band shortens
3. Z-lines come closer together - 53In terms of attachments of muscles to bones, skin, etc, describe the difference between "Origin" and "Insertion"O- Point of attachment of a muscle that is LEAST moveable
I- "" that is MOST moveable - 54Describe the difference b/t Agonist, Synergist, and AntagonistAgonist- Muscle whose contraction is primarily responsible for producing a movement
Synergist- Muscle that helps the Agonist work efficiently
Antagonist- Muscle whose action opposes the movement of the Agonist - 55Give an example of an: Agonist Antagonist SynergistTriceps brachii
Biceps brachii
Brachialis and Brachioradialis - 56Name 3 types of molecules that can move thru membrane w/o channel or protein carrierSmall, uncharged
Nonpolar/Lipid/Hydrophobic
Water - 57NaK Pump: How many of each ion is pumped and in which direction?3NO 2KIN
- 58Equation for Hydrolysis of ATPATP + H2O -----ATPase----> ADP + P + Energy
- 59Higher [Na] in or out of cell? K? Positive/Negative charges in/out of membrane?More Na outside of cell
More K inside of cell
Positive outside, Negative inside - 60Leak Channels: Usually open or closed? What causes it to open?Always open
- 61Ligand-gated Channels: Usually open or closed? What causes it to open?Closed
Ligand - 62Voltage-Gated Channels: Usually open or closed? What causes it to open?Closed
Voltage across membrane - 63Mechanically-gated Channels: Usually open or closed? What causes it to open?Open or close in response to Mechanical stimuli
- 64Units used to measure the potential energy in cellsMillivolts (mV)
- 65State the type of energy present in an electrical gradient and then what happens when the barrier separating the ions is removedPotential
Ions will follow their gradients, this creating a flow of electrical charges; Thus, Potential Energy is converted into Kinetic Energy - 66Define Polarized cell membraneCell Membrane with opposite charges on each side
- 67The _________ ____________ is the voltage measured across a cell membraneMembrane Potential
- 68Define Resting Membrane PotentialThe voltage measured across a cell membrane AT REST
- 69State the resting potential value in a skeletal muscle fiber and explain why it is either positive or negative-85mV
Negative b/c the negative charges inside the fiber outnumber the positive charges outside the fiber - 70Name the 3 factors that determine the resting membrane potential in a skeletal muscle fiber1. More K+ Leak channels than Na+ Leak channels
2. Neg. charged proteins/molecules in the cell
3. Na+K+ Pump moves more + out of the cell than it moves into the cell - 71Why is it important for the Na+K+ Pump to maintain a steep gradient in skeletal muscle fibers?B/a this allows Na+ and K+ to later move across the skeletal muscle fiber thru Na+VGC's and K+VGC's when stimulated by a motor neuron
- 72A quick, temporary change in the membrane potential of a cell is called what?Action Potential
- 73What are action potentials used for?Communicating w/ other cells or to cause a cell response (Like a Muscle contraction)
- 74Identify the 2 major types of channels that open and close during an action potential and what stimulates each type to open1. Ligand-gated Channels: ACh binding to the channel
2. Voltage-gated Channels: A change in voltage on the membrane - 75Define Depolarization & RepolarizationD- Membrane becomes the same charge on the inside and outside
R- Membrane returns to opposite charges on opposite sides - 76Is the Na+ VGC activation gate open or closed during: Rest? Depolarization? Repolarization?Closed
Open
Closed - 77Is the Na+ VGC inactivation gate open or closed during: Rest? Depolarization? Repolarization?Open
Open
Closed - 78Is the K+ VGC open or closed during: Rest? Depolarization? Repolarization?Closed
Closed
Open - 79Which ions are moving AND in which direction during: Rest? Depolarization? Repolarization?Rest: No movement
Dep: Na+ moving inside muscle fiber
Rep: K+ moving outside muscle fiber - 80Is membrane potential positive or negative during: Rest? Depolarization? Repolarization?Neg
Pos
Neg - 81Name the 3 phases involved in skeletal muscle contraction and briefly describe what happens in each1. Excitation Phase: Motor neuron stimulated end plate potential in the muscle fiber
2. Excitation-Contraction Coupling Phase: This causes an AP which quickly spreads throughout & thus the Cisternae release Ca+2
3. Muscle Contraction Phase- Ca+2 binds to Troponin and the thin myofilaments slide to the middle of the sarcomere - 82How many Neuromuscular Junctions does each Skeletal Muscle Fiber have?1
- 83Define the term "End-plate Potential" and state whether it's an action potential or graded potentialDefinition: Term describing the Depolarization of a motor end plate
Graded potential - 84Discuss the role of Ca+2 in both the Excitation phase and in the Contraction PhaseEP: Ca+2 bind to Synaptic vesicles, triggering them to release ACh into Synaptic Cleft
CP: Ca+2 binds to Troponin, setting the rest of the steps into motion - 85BRIEFLY summarize the 4 events that happen when a muscle relaxes1. ACh broken down, Sarcolemma repolarizes
2. Ca+2 channels in the Sarcoplasmic Reticulum close
3. Ca+2 pumped back into the SR by Calcium-ATPase
4. Tropomyosin blocks binding site on Actin so Ca+2 can't bind - 86Define the term "All-or-none Principle" and how it relates to muscle contractionPrinciple that says ALL sarcomeres shorten at the same time in a muscle contraction BUT if there isn't a sufficient stimulus then NONE of them will shorten
- 87Define "Motor Unit"One Somatic Motor Neuron and all of the muscle fibers it innervates
- 88Define "Muscle twitch"A single contraction-relaxation cycle
- 89Name the 3 phases of a muscle twitch and give a brief description of each1. Latent Period- First 1-2 ms after stimulus arrives
2. Contraction Phase- Cross bridges form and muscle shortens if the stimulus is great enough
3. Relaxation Phase- Ca+2 pumped back into SR and muscle returns to relaxed state - 90Define "Graded Muscle Response" In what 2 ways may a muscle contraction be graded?Variations in the degree or strength of muscle contraction in response to demand
1. Changing the FREQUENCY of stimulus
2. Changing the STRENGTH of stimulus - 91Describe what causes each of the following: Wave summation Incomplete/Unfused Tetanus Complete/Fused Tetanus1. A stimulus arriving while the muscle is still contracted
2. Stimuli keeps coming while the muscle is still contracted
3. Stimuli comes extremely rapidly while the muscle is contracted - 92What factors affect the force of muscle contraction? (4)1. # Motor Units recruited
2. Size of each muscle fiber
3. Asynchronous recruitment of Motor Units
4. Degree of Muscle Twitch - 93Name the 3 major functions of the Nervous System and briefly describe eachSensory Input- Sense change in environment
Integration- Receive, analyze, decide, send
Sensory Output- Receive, send response to Effector Organ - 94What type of Neuron is involved in: Sensory Input? Integration? Motor Output?Afferent/Sensory Neurons
Interneurons/Association Neurons
Efferent/Motor Neurons - 95Name the 2 components of the CNS Name the 3 components of the PNSBrain and Spinal Cord
Nerves, Ganglia, Sensory Receptors - 96Define each of the following: Nerves Ganglia Sensory Receptors-Bundles of Axons outside CNS organs
- Clusters of Cell Bodies outside CNS organs
- Dendrites of sensory Neurons that receive the stimulus and send it to the CNS - 97The PNS/Afferent Division can be split into what 2 Divisions?Somatic Sensory Division
Visceral Sensory Division - 98The PNS/Efferent Division can be split into what 2 Systems?Somatic Nervous System
Autonomic Nervous System - 99The Autonomic Nervous System can be split into what 2 Divisions?Sympathetic Division
Parasympathetic Nervous Division - 100Define "Proprioceptor"Sensory receptor in the Somatic Sensory Division that is responsible for being able to feel the stretch of muscles and joints
- 101Somatic Nervous System: Effector(s)? Voluntary or Involuntary Control?Skeletal Muscles
Voluntary - 102Autonomic Nervous System: Effector(s)? Voluntary or Involuntary Control?Effector Organs: Cardiac & Smooth Muscle, Glands, and Adipocytes
Involuntary - 103Sympathetic Division of Autonomic Nervous System: Nickname? Overall Function(s)?Fight or Flight
Mobilizes body during the 4 E's: Embarrassed, Excited, Exercise, Emergency - 104Parasympathetic Division of Autonomic Nervous System: Nickname? Overall Function(s)?Rest and Digest/Housekeeping
Conserve energy and promote housekeeping duties - 105Name the 2 major cells that make up Nervous TissueNeuroglia/Glia
Neurons - 106Neuron or Neuroglia? Electrically excitable cell Receive and send electrical signals Smallest one Can divide High metabolic rateNeuron
Neuron
Neuroglia
Neuroglia
Neuron - 107Neuron or Neuroglia? Structural and Functional unit of NS Do not divide Most numerous of the 2 cells Live a very long timeNeurons
Neurons
Neuroglia
Neurons - 108Function of: Dendrites? Cell Body? Axon Hillock?- Receive signal and send to Cell Body
- Receive signal and send to Axon Hillock
- Gather all signals, add them up, send to Axon - 109Function of: Axon/Nerve Fiber? Myelin Sheath? Nodes of Ranvier/Neurofibril Nodes? Synaptic Knob/Bulb/Terminal?- Receive signal and send to Synaptic Knob
- Covering around Axon to protect it from surrounding Neurons
- Speed up nerve impulse
- Receive signal and send to Effector Organ - 110Astrocytes: CNS or PNS? Structure? Function(s)?-CNS
-Star-shaped, extensions cling to Neurons and Capillaries
-Form blood-brain barrier, control levels or Na+ and K+, Anchor Neurons, Replace space of dead Neurons, Secrete chemicals and regulate connections b/t Neurons during development - 111Microglial Cells: CNS or PNS? Structure? Function(s)?-CNS
-Small and Rare
-Phagocytes- Eat Pathogens and dead Neurons - 112Ependymal Cells: CNS or PNS? Structure? Function(s)?- CNS
- Simple Cuboidal w/ Cilia, line Ventricles in CNS organs
- Form Cerebrospinal Fluid - 113Oligodendrocytes: CNS or PNS? Structure? Function(s)?- CNS
- Round cells w/ extensions that wrap CNS Neurons
- Form Myelin Sheath in CNS Neurons - 114Schwann Cells/Neurolemmocytes: CNS or PNS? Structure? Function(s)?- PNS
- Flattened cells that wrap around Axons in PNS Neurons
- Form Myelin Sheath in PNS Neurons - 115Satellite Cells: CNS or PNS? Structure? Function(s)?- PNS
- Flattened cells that wrap cell bodies within the Ganglia
- Regulate Nutrients - 116Compare the structure of: Multipolar Neurons Bipolar Neurons Unipolar Neurons- Many Dendrites, 1 Axon
- 1 Dendrite, 1 Axon off each side
- 1 Axon splits like a T, 1 Dendrite - 117Compare the Function(s) of: Sensory Neurons Motor Neurons Interneurons- Detect changes in Environment
- Carry motor commands to Effector Organs
- Integration - 118Compare the Function of: Somatic Sensory Neurons Visceral Sensory Neurons Somatic Motor Neurons Visceral/Autonomic Motor Neurons- Monitor Outside world and our position in it
- Monitor conditions in internal organs
- Send motor commands to Skeletal Muscles
- Send motor commands to Effector Organs - 119Define "Synapse" Compare location or electrical and chemical Synapses- Site of communication b/w Nerve cell and another cell
- Electrical: Smooth & Cardiac Muscle
Chemical: Basically everywhere else - 120List the basic steps of what happens at a chemical synapse starting w/ an AP arriving1. AP arrives at Presynaptic Neuron
2. Ca+2 enters
3. Synaptic vesicles Exocytose ACh
4. ACh binds to Receptor on postsynaptic neuron
5. IF receptor is Na+ VGC, the Na+ enters postsynaptic neuron
6. Ca+2 leave Presynaptic neuron, thus stopping release of more ACh
7. AchE break down ACh - 121List the basic steps of what happens in the Excitation-Contraction Coupling Phase, starting w/ an AP arriving1. AP arrives on Sarcolemma & spreads down T-Tubules
2. AP reaches Cisternae, twists DHP receptors
3. Ca+2 channels on the Cisternae, called Ryanodine receptors, open & cause Ca+2 to flow into Sarcoplasm
4. Ca+2 binds to Troponin &, at the same time, the Sarcolemma and T-Tubules are repolarized - 122List the basic steps of what happens in the Contraction Phase in Muscles1. Ca+2 bind to Troponin, Troponin moves Tropomyosin, Actin active site uncovered
2. Myosin head binds to Actin active site
3. ADP and P fall off, Myosin head moves thin filament
4. ATP binds to Myosin head to break crossbridge
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- Fichas sobre A & P Lecture Test #3, creado por Megan Shelton el 14/03/2018.
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