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Learning 2

Taher Miah Organisms & environment Inglés 15 fichas

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  1. 1Major input to the purkinje cells?•Parallel fibers
    •Climbing fibers
  2. 2Major input to granule cells?Mossy fibers
  3. 3Why do purkinje cells have lots of dendrites?Receive loads of info from granule cells
  4. 4Hippocampus important for:Spatial memory + word recall
  5. 5Long term potentiation (LTP)•Releasing a big stimulus
    •AP is higher/Lower in response
    •Sustained response
  6. 6The 3 major afferent pathways:•Dendate region
    •CA3
    CA1
  7. 7What are these 3 pathways known together asTrisynaptic circuit of hippocampus
  8. 8Electrophysiological recordings:•EC recording
    •IC recording
    •In vivo recording
  9. 9Receptors important for learning + memory?AMPAR + NMDAR (post synaptic receptors)
  10. 10Induction of LTP First stage1) Low levels of stimulation release glutamate, binds to AMPAR receptors=NA+ influx
  11. 11Second stageNMDAR receptors can’t open, Mg2+ ion blocking their pores
  12. 12Third stageLTP induction releases shit ton of glutamate, opens shit ton of AMPAR receptors= shit ton of Na+ influx
  13. 13Fourth stageDepolarisation of cell occurs, AMPAR receptors open as depolarisation is enough to remove Mg2+ ion
  14. 14Fifth stageNa+ and Ca2+ influx thru AMPAR receptors
  15. 15Sixth stage^Ca2+ enables long term change in responsiveness

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Organisms & environment Fichas sobre Learning 2, creado por Taher Miah el 05/05/2018.
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