Fichas
BCH Exam 2
Fichas del conjunto (19)
- 1Six catalytic strategiescovalent catalysis, acid base catalysis, nucleophilic substitution, metal ion catalysis, redox reactions, Transition state stabilization
- 2Examples of covalent catalysischymotrypsin and protein kinases
- 3Examples of serene proteasestrypsin, chymotrypsin, elastase
- 4The Catalytic Triad consists of:Histidine, Aspartic acid, Serine
- 5Chymotrypsin mechanismforms an acyl-enzyme covalent intermediate, involves acid base catalysis and is an example of hydrolysis
- 6What is required for the activity of chymotrypsin?serine 195 and Histidine 57
- 7Example of an oxidation reduction reaction:cytochrome c oxidase
- 8In serine proteases what is serine used for? What about Histidine?Serine is used for covalent catalysis and histidine is used for acid base catalysis
- 9Heme groupFe 2+ bound to a tetrapyrrole ring
- 10How is the heme group stabilizedthrough H bonding with a histidine residue
- 11What is a common characteristic of BPG, CO2 and H+ (protons)?They are allosteric effectors influencing Hb binding of O2
- 12Effect of BPG in hemoglobin-binds in the cavity between beta Hb subunits
-binds tightly to the T state but not the R state, stabilizing the T state and lowering the oxygen affinity of hemoglobin - 13Effect of protons and CO2 in hemoglobinThey promote the release of oxygen
- 14Bohr EffectThe regulation of O2 binding by H+ and CO2.
- 15Effects of carbamationstabilizes T-conformation (low affinity for Oxygen)
- 16The oxygen affinity of hemoglobin... as pH decreasesdecreases
- 17What type of aldoses are chiral?aldoses with 3C or more
- 18What types of ketoses are chiral?Ketoses with 4 C or more
- 19Pyranose vs furanosePyranose is a six member ring and furanose is a five member ring
Información
- Descripción
- Fichas sobre BCH Exam 2, creado por Amanda Flores el 14/11/2014.
- Creado por
- Amanda Flores · nov 2014
- Actualizado
- 19 feb 2016
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- 10
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