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Schistosomes (trematodes)

Jumael Zafar BIOL 123: Immunisation Inglés 13 fichas

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1DistributionEndemic > 70 tropical and sub-tropical countries
200 million people infected - 600 million people at risk
In sub-Saharan Africa >200 000 deaths per year
2The main species (major)S. mansoni (Africa)
S. haematobium (Africa and Middle East)
S. japonicum (S.E. Asia and China)
3Life cycleHere it is!!
41. Humans excreteHumans faece ad urinate eggs (diagnosis stage)
52. MiracidiaEggs hatch to release miracidia
63. Miracidia penetrationMiracidia penetrate snail tissue and form sporocysts in successive generations.
74. The cercariaeCercariae are released by snail and are free-living (infectious)
85. Humans swim in freshwaterCercariae penetrate through skin and lose tail becoming schistosomulae
96. CirculationCirculates in blood before migrating to hepatic blood and mature into adults
107. The paired adult worms (dioecious and sexually dimorphic)They migrate to mesenteric venules of bowel/rectum (laying eggs that circulate to the liver and shed in stools) venus plexus of the bladder.
11Clinical featuresCercarial dermatitis
Parasite maturation (acute schistosomiasis)
Established infection
Late stage infections
12DiagnosisEgg in stool or urine
Ultrasound
Bladder biopsy
Serological testing
13Treatment (Praziquantel)- Effective against trematodes (and cestodes)
- Single dose
- Few side effects
- Few contra-indications

Descripción: BIOL 123: Immunisation Fichas sobre Schistosomes (trematodes), creado por Jumael Zafar el 05/02/2019.
Creado por: Jumael Zafar · feb 2019
Actualizado: 6 feb 2019
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