Chapter 2 - FGI with Amine Synthesis

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Bruno lectures 3-4
Kerry Maltby
Creado por Kerry Maltby
Kerry Maltby
Creado por Kerry Maltby hace más de 10 años
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Resumen del Recurso

Pregunta Respuesta
SOCl_2
i) LiAlH_4 ii) Dilute HCl (work-up)
Via Imines
Via Azides
1) DMSO 2) LiAlH_4
1) LDA 2) LiAlH_4, Dilute HCl work-up
Reason for using biphasic conditions to avoid reaction between OH- and electrophile
Example of a biphasic solvent NaOH
What is a 'phase transfer' catalyst? base that is soluble in the organic phase that is used in a biphasic reaction mixture
Example of a 'phase transfer' catalyst BnEt_3NCl
1) azide, pthalimide, oxime 2) cyanide, nitromethane 3) acetonitrile
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