Secretory cells: Glands

Secretory cells: Glands

1. Function

   • Pancreas
     • Syn. store. secrete
       • CHONS
       • Complex Carbs
   • Salivary glands

2. Exocrine

   • Connection with surface epithelium
   • Tubular ducts

3. Endocrine

   • No connection with the surface
   • Ductless: secretion via bloodstream

4. Paracrine

   • Secretion into extracellular space
   • Tissue fluid

5. Ducts

   • Simple
     • Unbranched
       • Tubular
       • Coiled
     • Branched
       • Tubular
       • Acinar
   • Compound
     • Repeatedly branched
     • TAT
       • Tubular  Acinar  Tubuloacinar

6. Methods of secretion

   • Merocrine
     • Products leave with no loss of cellular material
   • Holocrine
     • Product is shed with the whole cell so the cell is destroyed
   • Apocrine
     • Product is discharged with the apical cytoplasm

7. Classification

   • Unicellular
     • Isolated cells
   • Multicellular
     • Cluster

8. Control of Glandular Activity

   • Neural
     • Salivary glands
   • Endocrine
   • Usually 1 form dominates
   • Pancreas- depends on the stimulation

9. Pinocytosis

   • Serous
     • Polyhedral/ Pyramidal
     • Immature--> Mature via dehydration
     • Pancreas, parotid salivary glands
   • Mucus
     • Goblet cells in SI
     • Contains mucin
     • Pale cytoplasm + dark-stained nucleus @ base
   • DNES/ Paracrine
     • Detected by immunocyctochem. methods
     • EM: Secreting cells show distinctive dense granules