Test
Wk 4: How to Treat Cardiovascular Disease
Preguntas del test (12)
1Which of the following will cause an increase in blood pressure?
- AIncreased parasympathetic nerve system activity at the sinoatrial node
- BVasodilatation of the peripheral arterioles
- CA decrease in circulating blood volume
- DIncreased activation of cardiac B1 (beta 1) adrenoreceptors
2Which of the following statements about the renin-angiotensin system is incorrect?
- AAngiotensin II is the major bioactive peptide
- BRenin is released from the kidney in response to an increase in blood pressure
- CActivation of the system can increase aldosterone production and Na+ retention
- DIncreased activity of ACE can lead to enhanced peripheral vasoconstriction
3Which of the following statements about hypertension is incorrect?
- AHypertension is a graded condition
- BHypertension is a major risk for heart failure and stroke
- CHypertension is usually due to a specific underlying pathology
- DHypertension is influenced by both genetic and lifestyle factors
4ACE inhibitors such as Catopril act by:
- ACompetitively antagonising AT1 receptors
- BDecreasing the formation of angiotensinogen
- CIncreasing the activity of renin
- DReducing the conversion of angiotensin I into angiotensin II
5Potential adverse effects (AEs) of calcium ion channel blockers such as Amlodopine do NOT include:
- ATachycardia
- BAnkle swelling
- CFlushing
- DOrthostatic hypotension
6Which of the following statements about anti-hypertensive drugs is INCORRECT?
- AAtenolol will oppose the increases in heart rate and contractility caused by SNS activation
- BHydrochlorothiazides act in the distal tubule to increase Na+ reabsoprtion
- CIrbesartan antagnoises AT1 receptors to reduce vasoconstriction
- DPrazosin reduces blood pressure by antagonising adrenoreceptors in the vasculature
7Eplerenone:
- AIncreases Na+ reabsorption in the collecting duct
- BProduces a large diuresis
- CReduces K+ excretion
- DIs a positive inotrope
8Which of the following does NOT contribute to the mechanism of action of Digoxin?
- AAn increase in intracellular Na+ concentrations
- BInhibition of the Na+-K+-ATPase
- CAn increase in cytoplasmic Ca2+
- DIncrease activity of the Na+-Ca2+ exchanger
9Organic nitraties such as Glyceryl Trinitrate do all of the following except:
- ACause vasodilation
- BIncrease cardiac contractility
- CReduce preload
- DLower blood pressure
10Cholesterol:
- AIs obtained exclusively from dietary sources
- BCan be transported from peripheral tissues to the liver by HDL
- CCirculates independently in the bloodstream
- DCan be synthesised in the adipose tissue
11Which of the following is NOT part of the mechanism of action for Statins?
- AIncreased uptake of LDL from plasma into hepatocytes
- BInhibition of HMA coA-reductase
- CReduction in endogenous cholesterol synthesis
- DDown regulation of LDL receptors
12In low doses, Asprin reduces platelet activation by:
- AReducing prostacyclin (PGl2) production
- BSelectively inhibiting cyclooxygenase in endothelial cells
- CPreventing the release of ADP
- DAcetylating COX1 in platelets
Información
- Descripción
- Lecture Topic: How to Treat Cardiovascular Disease
- Autor
- Julie Lam
- Idioma
- English
- Visitas
- 23
- Etiquetas
- Valoración
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