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PHSI3011 01-2 Cardiac excitation-contraction coupling 1 - Channels, exchangers, pumps

Michael Jardine 6 preguntas

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Preguntas del test (6)

  1. 1Which of the following is NOT a type of Calcium channel?
    1. AG-type
    2. BL-type
    3. CN-type
    4. DT-type
  2. 2An L-type Calcium channel has how many subunits?
    (each controlled by a separate gene)
    1. A2
    2. B3
    3. C4
    4. D5
    5. E6
    6. F7
    7. G8
  3. 3An L-type Calcium channel is highly selective for Calcium, but is also somewhat permeable to Sodium and Potassium.
    1. AVerdadero
    2. BFalso
  4. 4During diastole, the Na/Ca exchanger and the SR Ca pump both move Ca. Which way around?
    1. ANa/Ca exchanger will pull Ca IN to the myoplasm; the SR Ca pump will pump Ca back INTO the SR.
    2. BNa/Ca exchanger will pull Ca IN to the myoplasm; the SR Ca pump will pump Ca back OUT of the SR.
    3. CNa/Ca exchanger will push Ca OUT from the myoplasm; the SR Ca pump will pump Ca back INTO the SR.
    4. DNa/Ca exchanger will push Ca OUT from the myoplasm; the SR Ca pump will pump Ca back OUT of the SR.
  5. 5The longitudinal SR contains a high concentrations of proteins acting as an ATP-dependent Ca pump - returning Ca from the myoplasm to the SR lumen (to help terminate contraction).
    These proteins are called SERCA.
    What does SERCA stand for?
    [blank_start]S[blank_end] [blank_start]E[blank_end] [blank_start]R[blank_end] [blank_start]C[blank_end] [blank_start]A[blank_end]
    1. ASarco
    2. BSarcoplasmic
    3. CEndo
    4. DEndoplasmic
    5. E[plasmic] Reticulum
    6. F[plasmic] Ryanodine
    7. GCalcium
    8. HConcentration
    9. IActivation
    10. JActivator
    11. KAdjustment
    12. LATPase
  6. 6The role that Phospholamban plays in regulation of the SR Ca pump is:
    1. AInhibitory; cancelled when phosphorylated.
    2. BInhibitory; reinforced when phosphorylated.
    3. CPermissive; cancelled when phosphorylated.
    4. DPermissive; reinforced when phosphorylated.

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PHSI3011 01-2 Cardiac excitation-contraction coupling 1 - Channels, exchangers, pumps
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