Test
IBS Set 1 Quiz - DNA and Gene expression
Preguntas del test (31)
1Adenine complementary pairs to what other bases in DNA and RNA?
- ACytosine
- BGuanine
- CThymine
- DUracil
2What direction does the coding strand run in?
- A5' to 3'
- B3' to 5'
3What direction does the template strand run in?
- A5' to 3'
- B3' to 5'
4What is the correct process of DNA replication?
- ADNA helicase unwinds -> SSBP -> Primase -> DNA polymerase builds new DNA strand in 5' to 3' -> exonuclease removes primers -> DNA polymerase fills the gaps -> DNA ligase fixes gap in sugar-phosphate backbone.
- BDNA helicase unwinds -> SSBP -> Primase -> DNA polymerase builds new DNA strand in 3' to 5' -> exonuclease removes primers -> DNA polymerase fills the gaps -> DNA ligase fixes gap in sugar-phosphate backbone.
- CDNA gyrase unwinds -> SSBP -> Primase -> DNA polymerase builds new DNA strand in 5' to 3' -> exonuclease removes primers -> DNA polymerase fills the gaps -> DNA ligase fixes gap in sugar-phosphate backbone.
- DDNA gyrase unwinds -> SSBP -> Primase -> DNA polymerase builds new DNA strand in 3' to 5' -> exonuclease removes primers -> DNA ligase fills the gaps -> DNA ligase fixes gap in sugar-phosphate backbone.
5What is the function of Gyrase?
- APrevent DNA supercoiling
- BUnwind the double stranded DNA
- CRemove RNA primers
- DAdd DNA repeats to the 3' end of DNA strands in telomere regions (at the end of the chromosome)
6What is the function of telomerase?
- AAdd DNA repeats to the 3' end of DNA strands in telomere regions (at the end of the chromosome)
- BPrevents DNA supercoiling
- CUnwinds the DNA double strand
- DRemove RNA primers
7Which type of RNA encodes the amino acid sequence of a polypeptide?
- AmRNA
- BrRNA
- CtRNA
- DsnRNA
8Which type of RNA forms a protein complex which aid in the formation of a spliceosome?
- AmRNA
- BsnRNA
- CrRNA
- DtRNA
9Which type of RNA is a component of the ribosome?
- ArRNA
- BmRNA
- CtRNA
- DsnRNA
10Which type of RNA is responsible for bringing amino acids to the ribosomes during translation?
- AtRNA
- BrRNA
- CmRNA
- DsnRNA
11What does label 1 show on the model of the gene?
- APromoter
- BRNA coding sequence
- CTerminator
12What does label 2 show on the model of the gene?
- APromoter
- BRNA coding sequence
- CTerminator
13What does label 3 show on the model of the gene?
- APromoter
- BRNA coding sequence
- CTerminator
14The process of transcription is what?
- ADNA Helicase unwinds -> Gyrase alleviates supercoiling -> RNA polymerase binds to the promoter and starts in 5' to 3' -> Terminator is reached -> pre-mRNA is cleaved off -> DNA helix is reformed.
- BDNA Helicase unwinds -> Telomerase alleviates supercoiling -> RNA polymerase binds to the promoter and starts in 5' to 3' -> Terminator is reached -> pre-mRNA is cleaved off -> DNA helix is reformed.
- CDNA Helicase unwinds -> Gyrase alleviates supercoiling -> RNA polymerase binds to the promoter and starts in 3' to 5' -> Terminator is reached -> pre-mRNA is cleaved off -> DNA helix is reformed.
- DDNA Helicase unwinds -> Telomerase alleviates supercoiling -> RNA polymerase binds to the promoter and starts in 3' to 5' -> Terminator is reached -> pre-mRNA is cleaved off -> DNA helix is reformed.
15Splicing occurs in both prokaryotic and eukaryotic transcription.
- AVerdadero
- BFalso
16Select the processes which occur in the nucleus
- ADNA replication
- BTranscription
- CSplicing
- DTranslation
17Select the process which occurs in the cytoplasm
- ADNA replication
- BTranslation
- CTranscription
- DSplicing
18The start codon on mRNA is always what set of bases?
- AATG
- BTAC
- CAUG
- DAGU
19The 40s subunit of an 80s ribosome contains the P and A site where the tRNA binds.
- AVerdadero
- BFalso
20What is the process of amino acid charging?
- AAA attaches to amino-acyl tRNA synthetase -> ATP binds to docking site -> hydrolysed to AMP -> AMP exits -> tRNA becomes charged -> charged tRNA is released
- BAA attaches to amino-acyl tRNA synthetase -> ATP binds to docking site -> hydrolysed to ADP -> ADP exits -> tRNA becomes charged -> charged tRNA is released
21What is the process of translation?
- AMethionine-tRNA's anticodon UAC binds to the AUG sequence on mRNA -> Ribosome clamps to mRNA strand -> Peptide bond formation via Peptidyl transferase -> continuation -> STOP codon is reached -> release factor binds (no tRNA with anticodon) -> peptidyl transferase causes final protein to be ejected -> machinery disassembles
- BMethionine-tRNA's anticodon AUG binds to the UAC sequence on mRNA -> Ribosome clamps to rRNA strand -> Peptide bond formation via Peptidyl transferase -> continuation -> STOP codon is reached -> release factor binds (no tRNA with anticodon) -> peptidyl transferase causes final protein to be ejected -> machinery disassembles
- CMethionine-tRNA's anticodon AUG binds to the UAC sequence on mRNA -> Ribosome clamps to mRNA strand -> Peptide bond formation via Peptidyl transferase -> continuation -> STOP codon is reached -> release factor binds (no tRNA with anticodon) -> peptidyl transferase causes final protein to be ejected -> machinery disassembles
- DMethionine-tRNA's anticodon UAC binds to the AUG sequence on mRNA -> Ribosome clamps to mRNA strand -> Peptide bond formation via aminoacyl transferase -> continuation -> STOP codon is reached -> release factor binds (no tRNA with anticodon) -> peptidyl transferase causes final protein to be ejected -> machinery disassembles
22Convention is that polypeptides start with a C terminus and end with an N terminus.
- AVerdadero
- BFalso
23Polysomes are advantageous because they mean mRNA, which is very unstable, can be translated into many proteins despite having a short life span.
- AVerdadero
- BFalso
24What are the three generic types of DNA mutations?
- AInsertion
- BSubstitution
- CDeletion
- DRearrangement
- EReorderment
25What is meant by a silent mutation?
- AThe same amino acid is coded for, because although the base is substituted for a different one, the codon still codes for the same amino acid due to the degenerate nature of the triplet code.
- BA different amino acid is coded for for that particular triplet but the protein itself still remains functional.
- CA premature STOP codon is coded for by the substitution which leads to a truncated,, non functional protein.
26What is meant by a missense mutation?
- AThe same amino acid is coded for, because although the base is substituted for a different one, the codon still codes for the same amino acid due to the degenerate nature of the triplet code.
- BA different amino acid is coded for for that particular triplet but the protein itself still remains functional.
- CA premature STOP codon is coded for by the substitution which leads to a truncated,, non functional protein.
27What is meant by a nonsense mutation?
- AThe same amino acid is coded for, because although the base is substituted for a different one, the codon still codes for the same amino acid due to the degenerate nature of the triplet code.
- BA different amino acid is coded for for that particular triplet but the protein itself still remains functional.
- CA premature STOP codon is coded for by the substitution which leads to a truncated,, non functional protein.
28Deletion or insertion of 1,2,4 or 5 bases could cause a frameshift
- AVerdadero
- BFalso
29A frameshift can completely alter the primary structure of a protein.
- AVerdadero
- BFalso
30Most intronic mutations are not detrimental to the final protein.
- AVerdadero
- BFalso
31A missense mutation can produce a partially working protein.
- AVerdadero
- BFalso
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