11214253
Description
Flashcards by Sophia Puliasis, updated more than 1 year ago
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Created by Sophia Puliasis
over 6 years ago
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| Question | Answer |
| What are the key components of a signalling pathway? | Ligand, Receptor, Transducer & Effector |
| Name the 5 key developmental signalling pathways | Hedgehog Pathway Notch Pathway Wnt Pathway TGFB Pathway FGF Pathway |
| Name the ligand, receptor, transducer & effector of the hedgehog pathway | Ligand: Sonic hedgehog (Shh) receptor: patched transducer: Smoothered Effector: Gli (2 & 3) |
| Name the ligand, receptor, transducer & effector of the Notch pathway | ligand: Delta Receptor: Notch Transducer: NICD Effector: RBPjK |
| Name the ligand, receptor, transducer & effector of the Wnt Pathway | ligand: Wnt Receptor: frizzled/LRP transducer: Dishevelled effector: B-canetin |
| Name the ligand, receptor, transducer & effector of the FGF pathway | ligand: FGF receptor: FGFR transducer: ERK/AKT effector: ETS |
| How does cell signalling come about? | Endocrine: through bloodstream Paracrine: neighboring cells Autocrine: cell releases signal & captures it itself |
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