Cell Signalling lecture

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Cell signalling - Kim Dale (week 3)
Sophia Puliasis
Flashcards by Sophia Puliasis, updated more than 1 year ago
Sophia Puliasis
Created by Sophia Puliasis over 7 years ago
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Resource summary

Question Answer
What are the key components of a signalling pathway? Ligand, Receptor, Transducer & Effector
Name the 5 key developmental signalling pathways Hedgehog Pathway Notch Pathway Wnt Pathway TGFB Pathway FGF Pathway
Name the ligand, receptor, transducer & effector of the hedgehog pathway Ligand: Sonic hedgehog (Shh) receptor: patched transducer: Smoothered Effector: Gli (2 & 3)
Name the ligand, receptor, transducer & effector of the Notch pathway ligand: Delta Receptor: Notch Transducer: NICD Effector: RBPjK
Name the ligand, receptor, transducer & effector of the Wnt Pathway ligand: Wnt Receptor: frizzled/LRP transducer: Dishevelled effector: B-canetin
Name the ligand, receptor, transducer & effector of the FGF pathway ligand: FGF receptor: FGFR transducer: ERK/AKT effector: ETS
How does cell signalling come about? Endocrine: through bloodstream Paracrine: neighboring cells Autocrine: cell releases signal & captures it itself
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