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Flashcards

Cephazolin

Deleted user User has deleted their subject information English 15 cards

Cards in this deck (15)

  1. 1Trade namesKefzol - Cefazolin
  2. 2Chemical nameCephazolin sodium
  3. 3Therapeutic classanti-infective
  4. 4Pharmaceutical classantibiotic - cephalosporin
  5. 5Indications-Staphylococcal and streptococcal infections in people with mild-to-moderate penicillin allergy
    -Surgical prophylaxis
    -UTI
  6. 6ActionBactericidal; interferes with bacterial cell wall peptidoglycan synthesis by binding to penicillin-binding proteins, eventually leading to cell lysis and death.
  7. 7AbsorptionNot well absorbed in GIT - given via IV for optimal absorption
  8. 8DistributionDoes cross placenta and into breastmilk - however is said to be safe
  9. 9Metabolism & excretionExcreted unchanged in urine
  10. 10Half-life1.8 hours
  11. 11contraindications/precautions-Some people who are allergic to penicillins are also allergic to cephalosporins
    -Those with heart failure or on sodium restriction - high levels of sodium
    -Immunocompromised individuals = high incidence of rash
    -Renal impairment
  12. 12Adverse reactionsSkin: rash GIT: diarrhoea, N + V, CNS: neurotoxicity at high doses/ renal impairment
  13. 13Drug interactionsMay increase the effect of anticoagulants such as warfarin
  14. 14Nursing assessment implications-Obtain specimen for culture
    -Baseline vital signs
    -Monitor person's response to administration
  15. 15EducationTell patients to report adverse effects
    drink lots of fluids, and keep up nutrition

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Description
User has deleted their subject information Flashcards on Cephazolin, created by Deleted user on 04/06/2018.
Created by
Deleted user · Jun 2018
Updated
Jun 4, 2018
Views
11
History
  • Created by Em J · Jun 4, 2018
  • Copied by Em J · Jun 4, 2018
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