Flashcards
Gliclazide
Cards in this deck (11)
- 1Trade names- Diamicron- Glyade - Nidem (inc. MR)
- 2Pharmaceutical classSulfonylurea
- 3IndicationT2 DM
- 4ActionIncreases pancreatic insulin secretion
May decrease insulin resistance. - 5Absorption & distributionEasily absorbed in GIT - crosses placenta and enters breast milk
- 6Metabolism & excretionExtensively metabolised in the liver, metabolites excreted by the kidneys
- 7Half-life10.4 hours
- 8Contraindications & precaution- T1 DM & Ketoacidosis
- severe liver dysfunction
- Pregnancy
- Dose adjustment in renal impairment
- Caution use during acute illness such as MI - 9Adverse reactionsENDO: Hypoglycaemia Metabolic: weight gain GIT: discomfort, N & V SKIN: rash
- 10Medication/diet interactionsuse in combination with other antidiabetics can cause hypoglycaemia
- alcohol can cause hypoglycaemia
- corticosteroids, Beta2 agonists, thiazide diuretics & thyroid hormones can ^ BSL - 11EducationAdvise PT to take with food
Educate patient about diabetes (exercise, food) and consider referral to diabetes education
Education about hypoglycaemia symptoms
Instruct PT to drink glass of OJ if they notice signs of hypoglycaemia
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- User has deleted their subject information Flashcards on Gliclazide, created by Deleted user on 04/06/2018.
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- Created by Em J · Jun 4, 2018
- Copied by Em J · Jun 4, 2018
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