Flashcards
Glyceryl Trinitrate (GTN)
Cards in this deck (14)
- 1Trade names (at least 4)Anginine - Lycinate - Minitran - Nitrodur - Nitrolingual spray - Nitrostat
- 2Therapeutic classAntianginal
- 3Pharmaceutical classNitrate
- 4IndicationsAcute angina
Angina prophylaxis
Hypertension assoc. post-surgery - 5ActionReduces oxygen demand on the heart by reducing pre-load
Increases coronary blood flow - 6Therapeutic effectsDecreases BP and decreases pain assoc. with angina
- 7AbsorptionEasily absorbed dermally & sublingually - however PO does have a first pass effect and isn’t completely absorbed into the bloodstream
- 8Metabolism & excretionMetabolised by the liver and excreted by the kidneys
- 9Half-lifethree minutes
- 10Contraindications & precautionsHypovolaemia
Raised intracranial pressure
Significant anemia
Wear gloves when applying GTN patch - 11Adverse reactionsCVS: Hypotension, palpitation, peripheral oedema, tachycardia
CNS: Headache (treat w/ aspirin), dizziness, weakness
GIT: N & V
SKIN: rash - 12InteractionsCombined with antihypertensives can create an increased hypotensive effect
Alcohol use can lead to increased hypotension - 13Nursing assessmentsBP
Monitor vital signs
Pain assessment if required - 14EducationCaution pt to take drug as prescribed - discontinuation may cause coronary vasospasms
- Tell PT to take drug at first sign of chest pain
- Tablet needs to be held under tongue - ineffective if swallowed
- If pain persists after 10 minutes following 2 doses and rest - seek emergency med. Attention
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- User has deleted their subject information Flashcards on Glyceryl Trinitrate (GTN), created by Deleted user on 04/06/2018.
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- Created by Em J · Jun 4, 2018
- Copied by Em J · Jun 4, 2018
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