17870750
Description
Flashcards by Katerina Lalaouni, updated more than 1 year ago
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Created by Katerina Lalaouni
about 5 years ago
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| Question | Answer |
| Describe microscopic appearance of Burkholderia | Gram - Medium sized Rods Motile with one or more bipolar flagella(not B.mallei) DOES not produce any pigments |
| What are its optimal growth conditions? | Aerobic conditions No special requirements Grow well on MacConkey agar !B.mallei!needs glycerol in medium to grow |
| Catalase and Oxidase test results | Both positive |
| What are the virulent mechanisms of B.mallei? | +A capsule and type III and type IV secretion systems +A quorum antigenic variation system Capable of intracellular survival/spread can utilize actin based motility =Its presence causes a hypersensitivity reaction(crucial for its reaction) |
| What does the acute form of Glanders disease cause? | Forms yellow or grey nodules and ulcers in the respiratory tract or the skin. Its acute septicemic form ->Fever,mucopurulent nasal discharge and respiratory signs ->Death folllows within weeks |
| How many chronic clinical forms does Glanders disease have? | [3] -Nasal + -Respiratory + -Cutaneous form |
| Which form causes the so called "farcy" disease in Horses? | Skin form |
| Manifestation of Farcy disease | A lymphangitis ->where nodules start to develop through lymphatic vessels of the limbs ->Ulcers later on develop and release a yellowish pus |
| Is Glanders treatable? | Yes,but there is always the possibility of atb resistance (Chronically affected animals may survive for months or may recover and shed through the respiratory tract or skin) |
| Which form of the disease can show regional lymphadenopathy? | Nasal form:With ulcerative nodules on the mucosa of the nasal septum and lower part of the turbines |
| The ulcers in the nasal form when they heal leave____________ | Star shaped scars |
| How do lungs alter through Glanders? | Develop tubercule-like lesions |
| Which species causes Melioidosis? | Burkholderia pseudomallei |
| i)Second name for Melioidosis and ii)pathogenetic manifestation | i)Pseudoglanders ii)Pneumonia is the most common clinical presentation-chronic suppurative lesions in the lungs |
| What do you use for its detection? | Sample:Lesions,blood+ Cultivation:In MacConkey agar |
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