Flashcards
Signal transduction
Cards in this deck (6)
- 1second messengersSecond messengers are molecules that relay signals received at receptors on the cell surface — such as the arrival of protein hormones, growth factors, etc. — to target molecules in the cytosol and/or nucleus.
- 2cell responses to signal transductionmodulation of gene translation, hormone
secretion, energy production, cell division and cell
motion - 3examples of intracellular second messenger• Cyclic nucleotides such as cyclic AMP (cAMP) or
cyclic GMP (cGMP)
• Calcium ions
• Derivatives of Phosphatidylinositoltriphosphate
(PIP3): Inositol-triphosphate (IP3) and diacylglycerol
(DAG) - 4types of receptors-Ion channel
-G protein coupled
-enzyme coupled - 5ligand gated ion channelLigand-gated ion channels (LGICs) are a group of transmembrane ion channel proteins which open to allow ions such as Na+, K+, Ca2+, or Cl- to pass through the membrane in response to the binding of a chemical messenger (i.e. a ligand), such as a neurotransmitter.
- 6voltage gated ion channelsVoltage-gated ion channels are a class of transmembrane ion channels that are activated by changes in electrical membrane potential near the channel; these types of ion channels are especially critical in neurons, but are common in many types of cells.
Information
- Description
- Flashcards on Signal transduction, created by KirstyRM on 31/01/2015.
- Created by
- KirstyRM
- Views
- 0
- Rating