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Benign Prostatic Hyperplasia

Mark George English 9 cards

Cards in this deck (9)

  1. 1BPH Patho Static ComponentProliferation of Glandular Epithelium
    (alterations of testosterone, estrogen, DHT)
  2. 2BPH Patho Dynamic componentIncrease in prostatic smooth muscle tone linked to altered activity of PICs
    (possibly contributes to increased prostate contractility)
  3. 3BPH Pharmacology Finasteride5Alpha Reductase inhibitor
    Blocks conversion of testosterone into DHT
    Altered libido / Impotence
  4. 4BPH Pharmacology TamsulosinAlpha1a adrenoceptor antagonist
    blocks prostatic smooth muscle receptors :- decreases Ca++ availability
    (decreased prostate contractility)
    Postural hypotension / GIT
  5. 5BPH diagnostics DRE (digital rectal exam)Physical exam determines the state and size of the external surface of the prostate gland
  6. 6BPH Diagnostics PSABlood test that measures the level of specific antigen produced by both benign and malignant prostate tissue
  7. 7BPH Clinical Manifestations (Obstructive)proLONGed voiding.
    WEAK urinary stream.
    INCOMPLETE emptying.
    abdominal STRAINing.
    posturination DRIBBLE.
  8. 8BPH Clinical manifestations (Irritative)nocturia
    bladder PAIN
    URGENT urination
    incontinence
  9. 9BPH Clinical manifestations (Ureter obstruction)Bladder/kidney INFECTION
    acute urinary RETENTION
    RENAL INSUFFICIENcy
    HAEMATURIA

Information

Description
Pathophysiology, medications, CMs, Diagnostics
Created by
Mark George
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78
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