257873
Description
Flashcards by Mark George, updated more than 1 year ago
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Created by Mark George
over 10 years ago
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| Question | Answer |
| BPH Patho Static Component | Proliferation of Glandular Epithelium (alterations of testosterone, estrogen, DHT) |
| BPH Patho Dynamic component | Increase in prostatic smooth muscle tone linked to altered activity of PICs (possibly contributes to increased prostate contractility) |
| BPH Pharmacology Finasteride | 5Alpha Reductase inhibitor Blocks conversion of testosterone into DHT Altered libido / Impotence |
| BPH Pharmacology Tamsulosin | Alpha1a adrenoceptor antagonist blocks prostatic smooth muscle receptors :- decreases Ca++ availability (decreased prostate contractility) Postural hypotension / GIT |
| BPH diagnostics DRE (digital rectal exam) | Physical exam determines the state and size of the external surface of the prostate gland |
| BPH Diagnostics PSA | Blood test that measures the level of specific antigen produced by both benign and malignant prostate tissue |
| BPH Clinical Manifestations (Obstructive) | proLONGed voiding. WEAK urinary stream. INCOMPLETE emptying. abdominal STRAINing. posturination DRIBBLE. |
| BPH Clinical manifestations (Irritative) | nocturia bladder PAIN URGENT urination incontinence |
| BPH Clinical manifestations (Ureter obstruction) | Bladder/kidney INFECTION acute urinary RETENTION RENAL INSUFFICIENcy HAEMATURIA |
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