Movement of Kinesin

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Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312 almost 7 years ago
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Structural Basis for Biological Function (Molecular Motors) Flashcards on Movement of Kinesin, created by gina_evans0312 on 12/15/2013.

Resource summary

Question Answer
Step 1- Foreward Head hits new tubulin site Foreward head binds tightly and neck linker faces backwards
Step 2- ADP is released ADP is released and head is in stable 'nucleotide free' form
Step 3- ATP binds Neck linker binds to core motor of bound head
Step 4- Powerstroke Throws trailing head foreward so it binds to the next site
Step 5- ATP hydrolysis Pi is released, ADP bound head releases tubulin and the neck linker undocks
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