441811
Description
Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312
over 10 years ago
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| Question | Answer |
| Duty Ratio | How often the protein is in use |
| Processive | Follow distinct steps in order- no randomness |
| No of Myosin types | Approx 40 |
| Size of Myosin family core | 120kDa |
| Myosin Superfamily | G-protein (same as kinesin) |
| Myosin 2 | Muscle Myosin |
| Myosin V- Direction of movement | From minus end to plus end |
| Heavy/Light chains in Myosin V | 2 heavy, multiple light chains |
| Myosin V- Role of IQ motifs | To bend lever arm- keeps lever arm rigid & allows regulation |
| Myosin V-No of IQ motifs | 6 |
| Myosin V-N-terminus Motor | Globular myosin motor ATPase |
| Myosin V-Coiled coil neck | Links cargo binding domain to lever arms |
| Myosin V-Lever Arm | Contains 6 IQ motifs & 6 light chains |
| Myosin V- Light chain 8 | Part of cargo binding domain |
| Myosin V- Converter Domain | Where ATP cycle causes changes |
| Myosin V- Changes in converter domain are amplified by the | Lever arm |
| Movement of steps- same method for measurement as kinesin | |
| Myosin V- Length moved by each head | 72nm |
| Myosin V- Length moved by cargo | 36 nm |
| Myosin V- Change in angle of motor arms (pre/post stroke) | 70 degrees |
| Myosin V- Removal of one protein head | Causes failure of protein to work |
| Myosin V- Movement Model | Hand over Hand |
| Myosin V- Duty Ratio | High |
| Myosin V- Monomer? | Dimer |
| Myosin IV- Direction of Movement | From plus end to minus end |
| Myosin IV- No of IQ motifs | 2 |
| Myosin IV- Chains | 2 Heavy, multiple light |
| Myosin IV- Lever arm extension | Attached to actin binding heads with binding site for light chains of proximal tail |
| Myosin IV- N-terminal | Globular motor with special insert domain |
| Myosin IV- Proximal tail | Forms lever arm extension made of light chains and binds it to medial tail |
| Myosin IV- Medial tail | Coiled coil connecting lever arm extension to distail tail |
| Myosin IV- Distail tail | Connects medial tail and cargo binding domain |
| Myosin IV- C-terminus | Distal tail & cargo binding domains |
| Myosin IV- No of bound light chains | Same as Myosin II |
| Myosin IV- Step size | 36nm |
| Myosin IV- Role of light chains | No of light chains involved regulates level of movement More = more movement |
| Myosin IV- Adding Insert | Causes light chain binding region to move in opposite direction to Myosin V |
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