46781
Flashcards by Mark Arsenal, updated more than 1 year ago
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Created by Mark Arsenal
almost 8 years ago
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Description
| Question | Answer |
| What factors inhibit and stimulate Glycogen Synthase (form alpha 1-4 bonds)? | Stimulate: Glucose-6-Phosphate, Adrenaline, Insulin. Inhibit: Glucagon, Ca |
| What role does UDP-Glucose play? and how do we form it? | UDP-Glucose is the handle used to form alpha 1-4 bonds. We form it through Uridine (UTP) and Glucose-1 Phosphate combining (through enzyme UDP-Glucose Pyrophosphoryllase) forming UDP-Glucose and 2Pi. |
| What is Glycogenesis? | Formation of Glycogen |
| How do we form Alpha 1-4 bonds? | UDP-Glucose (Uridine+2Pi) acts as the glue to form the bonds. UDP-Glucose is formed through the breakdown of UTP-Glucose by the enzyme UDP-Glucose Phosphorylase. |
| How do we form Alpha 1-6 bonds? | We form 1-6 bonds by Glycogen Synthase which activates a branching enzyme which causes the linear glucose chain to snap and reattach forming a branch. |
| What role does Insulin play? | When Insulin levels are high (High Glucose) we form glucose through Glycogenesis. When Insulin is low (Low Glucose) we form glucose through Glycogenolysis. |