Definitions

Question	Answer
ANTIBACTERIAL	a synthetic or natural agent that kills bacteria
ANTIBIOTIC	naturally occurring antibacterial (penicillin)
BACTERICIDAL	an antibiotic that kill bacteria
BACTERIOSTATIC	an antibiotic that stops the growth of bacteria
CHEMOTHERAPY	use of chemicals that can directly affect microorganisms at concentrations that are tolerable to the host
CHEMOTHERAPEUTIC AGENTS	selectively toxic to parasitic organisms which invade the body
IN VITRO	biological process that can be made to occur outside the body
IN VIVO	biological process that occurs inside the body
AGONIST	substance that interacts with specific cellular constituent and elicits an observable response
ANTAGONIST	inhibits the effect of an agonist but no biological activity
THERAPEUTIC INDEX (definition)	how much can be given to cure the patient/chemotherapeutic index (ideally > 1)
THERAPEUTIC INDEX (formula)	Lethal Dose for 50% of patients ---------------------------------------------------------- Effective Dose for 50% of patients
CHEMOTHERAPEUTIC INDEX	minimum curative dose ---------------------------------------------------------- maximum tolerate dose
PRODRUG	a molecule that is inactive by itself, however transforms once it has an interaction with an enzyme and thus becomes active in the body
DRUG STABILITY	can increase in vivo stability and prolong action OR can decrease in vivo stability and prevent potential toxicity

Resource summary

	Created by Valentina Valenz almost 8 years ago