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PHRM 590 | Pharmacy Practice 1 | Pharmaceutics with Dr. Rao
Cards in this deck (17)
- 1What is pharmaceutics?Science of dosage form design
- 2Drug?Active chemical of drugs
- 3Dosage form?Formulation
Drug with inert ingredients - 4Examples of Liquids?Solutions, emulsions, suspensions
- 5Examples of Solids?Ointments, creams, pastes, gels
- 6Examples of Semi-Solids?Powders, granules, capsules, tablets
- 7Drug Delivery System?Drug in dosage form intended for a particular purpose or Route of Administration
- 8What are the different Routes of Administration?
- 9What is bioavailability?Unit-less value, often in percent
"Fraction of admin dose that reaches physiological activity usually determines onset and extent, AUC determines duration of Action - 10What are colligative properties?Dependent on total number of species in solution, (solute + solvent)
Examples; Boil Point, Freezing Point, Water Vapor, etc.. - 11What happens to blood cells when exposed to the following; hypotonic, isotonic, hypertonic solutions?Hypotonic? solute concentration lowers outside, cells will swell and burst
Isotonic? solute concentration is equal
Hypertonic? solute concentration is higher inside, cells shrink and shrivel - 12Determine the number of species a drug molecule will dissociate into; "glucose"Non-Electrolyte
**There is only one species here due to only being a solute present in product, also there is not another component to the chemical** - 13Determine the number of species a drug molecule will dissociate into; "Dextrose"Non-Electrolyte
**There is only one species here due to only being a solute present in product, also there is not another component to the chemical** - 14Determine the number of species a drug molecule will dissociate into; "Urea"Non-Electrolyte
**There is only one species here due to only being a solute present in product, also there is not another component to the chemical** - 15Determine the number of species a drug molecule will dissociate into; "Ranitidine HCl"Weak-Base
**There are 3 species here, one is the entire chemical, and then one from the Active Drug itself and then one from the salt** - 16Determine the number of species a drug molecule will dissociate into; "Homatropine HBr"Weak-Base
**There are 3 species here, one is the entire chemical, and then one from the Active Drug itself and then one from the salt** - 17What is the relationship between MW and molecular size?MW = Total weight of molecule when you add up each component
Molecular Size = Size of the molecules
Direct Relationship between 2 values
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- PHRM 590 | Pharmacy Practice 1 | Pharmaceutics with Dr. Rao
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- Austin Thomas
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