Cancer Chemotherapy

Question	Answer
Name of cell-cycle specific drugs and their effect?	Antimetabolites Effective for high-growth-fraction malignancies
Name of cell-cycle non-specific drugs and their effects?	Alkylating agents Effective for both low-growth-fraction malginancies (such as tumours) and high-growth-fraction malignancies
What type of enzyme is telomerase?	A reverse transcriptase bound to RNA
Whah function does RNA have for telomerase to work?	Acts as a template for extension of the 3' end of the parental strand
What is myelosuppression?	Suppression of the bone marrow, resulting in decrease in white/red blood cells and platelet count
What three -cytes are reduced as a result of myelosuppression?	Leukocytes (white) Erythrocytes (red) Thrombocytes (platelets)
What is neutropenia?	A granulocyte disorder where there is an abnormally low number of neutrophils
what is ALL?	Acute Lymphoblastic Leukaemia

Resource summary

	Created by bsmith.1994 about 10 years ago