Biology - Risk of Cardiovascular Disease 1

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Mind Map on Biology - Risk of Cardiovascular Disease 1, created by izzykersley01 on 10/29/2014.
izzykersley01
Mind Map by izzykersley01, updated more than 1 year ago
izzykersley01
Created by izzykersley01 over 10 years ago
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Resource summary

Biology - Risk of Cardiovascular Disease 1
  1. Risk?
    1. 'The probability of occurrence of some unwanted event or outcome'
      1. Example calculation of risk: 19,429 UK people died of an injury/poisoning in 2005. Total population at the time was 60,209,408, so we can calculate this as an average risk
        1. 19,429 in 60,209,408... OR 1 in 60,209,408÷19,429 --> =1 in 3099 --> =1÷3099 --> =0.00032 OR 0.032%
      2. Factors that Increase the Risk of Cardiovascular Disease
        1. Lifestyle
          1. DIET - high in saturated fat increases blood cholesterol level, which increases atheroma formation. High salt levels increase blood pressure
            1. HIGH BLOOD PRESURE - increased risk of damage to artery walls
              1. Other causes include excessive alcohol consumption, stress and diet
              2. SMOKING - carbon monoxide combines with HAEMOGLOBIN in the blood, reducing the amount of oxygen being transported
                1. NICOTINE makes platelets more sticky so blot clots can form easily
                  1. Amount of ANTIOXIDANTS (help protect cells) in the blood decreases - increased risk of CVD
                  2. INACTIVITY - lack of exercise leads to high blood pressure
                  3. Beyond Our Control
                    1. GENETICS - some people inherit particular alleles which make them more likely to have high blood pressure or high cholesterol levels
                      1. AGE - increased age increases the risk of CVD
                        1. GENDER - men are at greater risk
                      2. High Blood Pressure (Hypertension)
                        1. Measure of the hydrostatic force of the blood against blood vessel walls
                          1. A SPHYGMOMANOMETER measures blood pressure - for a healthy average person the reading should be 100-140mmHg for SYSTOLIC pressure and 60-90mmHg for DIASTOLIC pressure
                            1. What determines your blood pressure?
                              1. Contact between blood and vessel walls causes FRICTION and effects the flow of blood - PERIPHERAL RESISTANCE
                                1. ARTERIOLES and CAPILLARIES have greater total SURFACE AREAS --> more friction --> more resistance --> slower blood flow --> lower pressure
                                2. If the walls of an artery/arteriole contract, the vessel contracts, increasing resistance
                                  1. If they relax, the lumen is dilated, so the resistance falls
                                  2. OEDEMA - fluid building up in tissues and causing swelling
                                    1. At the arterial end of a capillary, blood is under pressure. This forces fluid through the capillary walls into the intercellular spaces, forming TISSUE FLUID
                                      1. The capillary walls prevent blood cells and larger plasma proteins from passing through though
                                        1. High blood pressure means more of the fluid is forced out of the capillaries
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