I always feel fatigued and tired

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Biology Mind Map on I always feel fatigued and tired, created by ashraf Elsayed on 17/02/2019.
ashraf Elsayed
Mind Map by ashraf Elsayed, updated more than 1 year ago More Less
ashraf Elsayed
Created by ashraf Elsayed about 5 years ago
ashraf Elsayed
Copied by ashraf Elsayed about 5 years ago
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Resource summary

I always feel fatigued and tired
  1. Causes of fatigue
    1. Post viral infection
      1. Endocrine
        1. Hypothroidism
          1. Addisons
          2. Organ failure
            1. Heart failure
            2. Neoplastic
              1. Chronic infecetion
                1. TB
                2. Chronic inflammatory diseases
                  1. Crohn's disease
                3. Physiology of defecation
                  1. Several steps
                  2. Types of colorectal cancer
                    1. Squamous cell carcinoma
                      1. Cloacogenic carcinoma
                        1. Adenocarcinoma
                          1. Rare
                            1. Basal cell carcinoma
                              1. Melanoma
                              2. Risk factors
                                1. Age
                                  1. Male gender
                                    1. Smoking
                                      1. Obesity
                                        1. Heriditary polyposis syndromes
                                          1. First degree relatives with colon cancer
                                            1. Diet factors
                                            2. Pathogenesis
                                              1. Two pathways
                                                1. Adenoma-carcinoma sequence
                                                  1. Mutation of both copies of APC
                                                    1. K-ras mutation
                                                      1. P53 mutation and increased COX 2
                                                        1. Carcinoma
                                                        2. Polyp formation
                                                        3. Increased risk for polyp
                                                      2. MSI
                                                        1. Mutations of mismatch repair enzyme
                                                          1. Accumalation of several mutation
                                                    2. Signs and symptoms
                                                      1. Change in bowel habits
                                                        1. Difficulty in relieving oneself
                                                          1. Rectal bleeding
                                                            1. Cramping
                                                              1. Fatigue
                                                                1. Unintentional weight loss
                                                                2. Investigations
                                                                  1. Colonscopy
                                                                    1. CT scan
                                                                      1. Laboratory tests
                                                                        1. CBC
                                                                          1. Tumor markers
                                                                            1. CEA
                                                                        2. Staging and grading
                                                                            1. Mangement
                                                                              1. FOLFOX
                                                                                1. 5-Flurouracil
                                                                                  1. Leucoverin
                                                                                    1. Oxaloplatin
                                                                                    2. CAPOX
                                                                                      1. Capcitabeine
                                                                                      2. Surgical
                                                                                        1. Excision of the mass
                                                                                          1. Local
                                                                                            1. Total
                                                                                        2. Screening
                                                                                          1. Age 45 and above
                                                                                            1. Relatives with colorectal cancer
                                                                                            2. Epidemiology
                                                                                            3. Anatomy of large intestine
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