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gout

Description

Mind Map on gout, created by Salma Moustafa on 01/04/2019.
Salma Moustafa
Mind Map by Salma Moustafa, updated more than 1 year ago
Salma Moustafa
Created by Salma Moustafa about 5 years ago
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Resource summary

gout
  1. types of arthritis
    1. why
      1. deposition of monosodium urate crystals in joint
      2. risk factors
        1. ifestyle modifications
          1. medical conditions
            1. certain medications
              1. family history
                1. age and sex
                2. pathogenesis
                  1. phagocytosis by monoxytes
                    1. il1
                      1. il6
                        1. tnf
                          1. il8
                          2. neutrophil chemotaxis
                            1. lt
                              1. prostaglandins
                            2. classifications
                              1. primary
                                1. diet
                                  1. enzyme
                                  2. secondary
                                    1. renal failure
                                      1. malignancy
                                        1. inborn errors of metabolism
                                        2. vs pseudogout
                                        3. investigations
                                          1. cbc
                                            1. uric acid
                                              1. bmp
                                                1. synovial fluid analysis
                                                  1. urine
                                                    1. rheumatoid factor
                                                      1. ana
                                                        1. rf
                                                        2. non lab
                                                          1. xrays
                                                            1. ultrasound
                                                              1. ct scan
                                                                1. mri
                                                              2. management
                                                                1. allopourinol
                                                                  1. xanthine oxidase inhibitor
                                                                  2. probenecid
                                                                    1. increase uric acid excretion
                                                                    2. colchicine
                                                                      1. inhibit leukocyte entry
                                                                      2. nsaids
                                                                        1. pain relief
                                                                        2. acute
                                                                          1. nsaids
                                                                            1. sterids
                                                                              1. olchicine
                                                                              2. prophylaxis
                                                                                1. provenecid
                                                                                  1. allpopurinol
                                                                                2. prevention
                                                                                  1. diet
                                                                                    1. dialysis
                                                                                      1. reduce meat
                                                                                        1. reduce fish
                                                                                          1. reduce wine

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