Action potential (ms mV)

Resting potential/ polarised
1. ATP pump, 2K+in, 3Na+out
2. -60mV potential difference inside membrane compared to outside membrane means it is polarised
3. More permeable to K+ than Na+
4. Kinetic E. opens Na+ channels
  1. Na+ floods in down electrochemical gradient, converting it to electrical E.
    1. If it reaches -50mV (threshold potential) then will go to depolarisation
  2. (Na+ and K+ gated channels were both closed before)
5. (net - inside, net + outside)
6. K+channels open, K+ going out
Depolarisation
1. ATP pump, 2K+in, 3Na+out
2. K+channels open, K+ going out
3. +40mV potential difference inside membrane compared to outside membrane means it is depolarised
4. (net + inside, net - outside)
Repolarisation
1. ATP pump, 2K+in, 3Na+out
2. K+channels open, K+ going out
3. K+ gated channels open, K+ flows out down electrochemical gradient
  1. More flows out than needed meaning it becomes hyperpolarised
Hyperpolarisation
1. ATP pump, 2K+in, 3Na+out, and permeability starts to restore balance
  1. (Not able to register any more pain until back to resting potential)
2. K+channels open, K+ going out
3. K+ gated channels close

Resource summary

	Created by abigail8900 over 9 years ago