Splenic Disorders

melian.yates
Mind Map by melian.yates, updated more than 1 year ago
melian.yates
Created by melian.yates over 6 years ago
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Doctorate Pathology (Systems Pathology) Mind Map on Splenic Disorders, created by melian.yates on 10/22/2013.
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Splenic Disorders
1 Splenomegaly
1.1 Classify by:
1.1.1 Nature of the Enlargement
1.1.1.1 Uniform or Nodular
1.1.1.2 The consistency of the tissue
1.1.1.2.1 Wet/Blood or Firm
1.2 Uniform Enlargement
1.2.1 Wet Consistency
1.2.1.1 Lots of blood on cut section
1.2.1.2 Congestion
1.2.1.2.1 Ex. Portal Hypertension
1.2.1.3 Barbituate Euthanasia
1.2.1.4 Torsion
1.2.1.4.1 Gastric Dilation & Torsion (Takes spleen w/ it)
1.2.1.5 Anthrax
1.2.2 Firm Consistency
1.2.2.1 Chronic Stimulation (Anaemia, Infectious Disease)
1.2.2.1.1 Diffuse Neoplasia
1.2.2.1.1.1 Extramedullary Hematopoesis
1.3 Nodular
1.3.1 Wet Consistency
1.3.1.1 Heamatoma
1.3.1.1.1 Neoplasia
1.3.1.1.1.1 Especially Haemangioma/ haemangiosarcoma
1.3.1.1.1.1.1 Haemangioma
1.3.1.1.1.1.2 Haemangiosarcoma
1.3.1.1.1.1.2.1 Primary Sites (Canine):
1.3.1.1.1.1.2.1.1 Spleen
1.3.1.1.1.1.2.1.1.1 RT Atrium
1.3.1.1.1.1.2.1.1.1.1 Liver (can be 1st & 2ndary site)
1.3.1.1.1.1.2.1.1.1.1.1 Skin
1.3.1.1.2 Common, usually singular
1.3.2 Firm Consistency
1.3.2.1 Nodular Hyperplasia
1.3.2.1.1 Non vascular(Mesenchymal) neoplsia/ metastasis
1.3.2.1.1.1 Inflammation/Abscesses
1.3.2.1.1.1.1 Ex. Rhodococcus equi, Arcanobacterium pyogenes, Strep equi, Bovine traumatic reticuloperitonitis
1.3.2.1.1.2 Fibrosarcoma
1.3.2.1.1.2.1 Fibrocytes
1.3.2.1.1.3 Leimyosarcoma
1.3.2.1.1.3.1 Smooth muscle cells
1.3.2.1.2 Benign Nodular Hyperplasia is very common in old dogs
1.3.3 Metastases to the Spleen
1.3.3.1 Ex. Malignant Melanoma
2 Atrophy (Ageing/Wasting)
3 Contraction ex. Shock
4 Splenic Rupture
4.1 Splattered spleen syndrome
5 Siderofibrotic plaques/gamma-gandy bodies
6 Haemosiderin deposits
7 Infarcts
7.1 In peripheral (subcapsular) zones most prone
7.2 Where spleen is distended w/ blood, more prone to infarction
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