Asthma & COPD drugs

Description

Pharmacology Mind Map on Asthma & COPD drugs, created by brosenb1 on 30/10/2013.
brosenb1
Mind Map by brosenb1, updated more than 1 year ago
brosenb1
Created by brosenb1 over 10 years ago
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Resource summary

Asthma & COPD drugs
  1. Bronchodilators
    1. Beta Ad-Sympathomimetics
      1. NON-selective
        1. Short Acting
          1. Anaphylaxis & Acute attack
            1. cAMP
              1. Bronchodilator and Vasoconstrictor
                1. Fixes runny nose and allows breathing
              2. Epinephrine
              3. Bronchodilation: Chronic Asthma
                1. Nervous, tremors, flush, HA, tachycardia, Palpitations, Hypertension
                  1. Isoprpterenol
            2. Selective Beta 2 Agonist
              1. Short Acting
                1. cAMP
                  1. Before Triggering Activity
                    1. Rescue Drug
                      1. Albuterol
                        1. Tremors, nervous, restless, anxious, HA, tachycardia, palpitations, dysrhythmias, HYPERGLYCEMIA
                        2. cAMP
                          1. Narrow Angle Glaucoma
                            1. TACHYCARDIA, HYPERTENSION, HYPERGLYCEMIA, tremors, cardiac arrest, paradox-bronchoconstriction
                            2. Terbutaline, Metaproterenol
                          2. Long Acting
                        3. Anticholinergics
                          1. Short Acting
                            1. Prophylactic
                              1. PNS inhibit SNS Dominate
                                1. Norepinephrine release-->beta 2 receptors
                                  1. Narrow Angle GlaucomaOverdose: blurred vision, eye pain, HA, palpitations, N, insomnia, tremors
                                    1. Relieves AND Prevents asthma
                                  2. Ipratropium
                              2. Xanthines
                                1. Long-Acting=Maintenance
                                  1. cAMP
                                    1. 10-20 >20=toxicity
                                      1. Don't use if Seizure, cardiac, renal, liver disorders
                                        1. S/E: Dysrhythmias, Nervous, Irritable, flush, Dizzy, HYPOTENSION, seizures, GI distress, intestinal bleeding, HYPERGYLCEMIA, tachycardia, palpitations, cardiorespiratory collapse.
                                          1. Theophylline and Aminophylline
                              3. Anti-Inflammatory
                                1. Steroids
                                  1. Corticosteriods
                                    1. Prevention: slow onset
                                      1. Fluticasone
                                        1. Tremors, nervous, tachycardia
                                      2. Glucocorticoids
                                        1. Acute short Term Control
                                          1. Prednisone
                                            1. Numerous: GI ulcers, fat redistribution, weight gain, hyperglycemia,
                                              1. Take with food and taper off if been taking long term
                                        2. Mast Cell Stabilizers
                                          1. Prophylactic
                                            1. Prevention and Maintenance
                                              1. Suppresses Histamine release by stabilizing mast cells
                                                1. Cough, bad taste, rebound bronchospasm w/ long term use.
                                                2. Nedocromil & Cromolyn
                                            2. Leukotrienes
                                              1. Prophylactic
                                                1. Block leukotriene receptors
                                                  1. Slow onset: Prevention & Maintenance
                                                    1. Dizzyness, HA, GI distress, abnormal liver enzymes, nasal congestion, cough and pharyngitis
                                            3. Mucolytics
                                              1. Loosen mucus
                                                1. Acetaminophen overdose
                                                  1. 5 mins after bronchodilator and dilute in juice or soft drink
                                                    1. Mucomyst
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